Process Development Senior Scientist

Process Development Senior Scientist

In this vital role you will join the Drug Substance Technologies – Synthetics (DSTS) group within Process Development at our Cambridge, Massachusetts site. The DSTS organization is responsible for the invention, development, and implementation of innovative drug substance manufacturing processes and technologies that advance Amgen’s growing portfolio of small molecule and hybrid therapeutics. Our process chemists leverage deep expertise in organic chemistry to design efficient synthetic routes and scalable chemical processes that support drug substance manufacturing from early through late-stage development.

The successful candidate will be a collaborative, scientifically driven individual with strong expertise in organic chemistry, a passion for innovation, and a demonstrated record of scientific achievement.

• Design and develop synthetic routes and scalable chemical processes for the manufacture of synthetic and hybrid drug substances
• Develop safe, robust, efficient, and cost-effective manufacturing processes suitable for clinical and commercial production
• Advance enabling technologies that accelerate pharmaceutical development and improve sustainability, efficiency, and process robustness
• Support cGMP manufacturing activities and assist with technology transfer efforts to internal manufacturing sites and external contract manufacturing organizations (CMOs)
• Build process understanding through experimentation, process characterization, modeling, and data analysis to ensure consistent process performance
• Contribute to cross-functional drug substance development teams by providing technical expertise, experimental data, scientific recommendations, and clear documentation
• Collaborate across disciplines to support regulatory filings and author technical sections of regulatory documentation
• Stay current with advances in synthetic organic chemistry, process chemistry, and related technologies, and apply new scientific insights to ongoing programs
• Effectively collaborate within multidisciplinary teams that include chemists, engineers, analytical scientists, and other technical experts
• Independently manage project activities and deliver high-quality results within established timelines

We are all different, yet we all use our unique contributions to serve patients. The Scientific professional we seek is an individual with these qualifications.

• Doctorate degree PhD OR Pharm
  
  D OR MD [and relevant post-doc where applicable] completed by August 2026
• Master’s degree and 3 years of Scientific experience
• Bachelor’s degree and 5 years of Scientific experience

• Ph.D. in Organic Chemistry with expertise in total synthesis, reaction methodology, mechanistic chemistry, and/or process development
• Postdoctoral experience in academia or the pharmaceutical/biotechnology industry
• Experience with ADC, peptides
• Demonstrated track record of scientific innovation through peer-reviewed publications, patents, and/or conference presentations
• Strong problem-solving skills and ability to work effectively in a dynamic, interdisciplinary research environment
• Excellent written and verbal communication skills, with strong organizational and time management abilities
• Ability to manage multiple priorities and drive complex projects to completion
• A research summary submitted with the CV is strongly encouraged

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable…