Senior Engineer, Molecule Process Development and Manufacturing

About This Role

We are seeking a highly motivated and creative Chemical Engineer to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to develop robust processes for the synthesis of a wide range of assets across various modalities. As a Senior Engineer, you will gain experience in early to late‑phase drug development and exposure to designing and developing manufacturing processes for clinical and commercial therapeutics.

You will collaborate with a team of organic chemists and chemical engineers in designing innovative processes that supply new medicines to patients.

• Collaborate with development and manufacturing teams to design and conduct laboratory experiments aimed at optimizing and characterizing processes.
• Design and execute experiments to advance the portfolio, analyzing and sharing data to implement efficient and robust chemical processes.
• Manage key laboratory instrumentation.
• Develop fundamental process knowledge for transitioning processes from lab scale to manufacturing partners.
• Collaborate with Process Chemistry, Analytical Chemistry, Solid Form, and Separations colleagues to support clinical material supply and regulatory filings.
• Write research reports, present data in team meetings, and engage in CMC activities, including authoring CMC sections of INDs.
• Interact with Contract Research Organizations as project needs evolve.
• Initiate innovative research projects to improve process understanding and control.
• Mentor and guide earlier career team members.

You have a passion for exploring novel scientific concepts and are eager to contribute to the design, development, and execution of cutting‑edge technologies in the service of delivering drug candidates for clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors, ultimately impacting patient lives. You thrive in a collaborative environment where urgency, accountability, inclusion, and integrity are shared values.

• Ph.D. with 5+ years of relevant experience.
• M.S. with 6+ years of relevant experience in pharmaceutical or biotech settings.
• BS with 7+ years of relevant experience in pharmaceutical or biotech settings.
• Strong background in pharmaceutical chemical engineering, including crystallization techniques, process characterization, process safety, and tech transfer protocols.
• Experience in crystallization of APIs and familiarity with analytical tools and purification techniques.
• Ability to work both independently and collaboratively.
• Good communication skills and the desire to work in a collaborative team environment.

• Experience with process characterization, crystallization techniques, drug substance form control, and familiarity with process safety protocols.
• Demonstrated problem‑solving skills in pharmaceutical chemical engineering.

Management

• Base compensation range: $–$.
• Regular employees are eligible to receive short‑term and long‑term incentives, including cash bonus and equity incentive opportunities.
• Benefits include medical, dental, vision, and life insurance; fitness and wellness programs; short‑ and long‑term disability insurance; paid vacation; sick time; paid maternity and parental leave; 401(k) with company match; employee stock purchase plan; tuition reimbursement up to $10,000 per year; employee resource group participation.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E‑Verify Employer in the United States.