Expedition Medicines | Cambridge, MA Expedition Medicines: Vice President, Finance

Vice President of Finance

Cambridge, MA

Oversee all aspects of accounting, financial operations, and compliance while contributing meaningfully to corporate strategy and long‑term planning. This is a key leadership role and is the primary steward of the company’s financial strategy, discipline, systems, and governance.

• Oversee and manage all accounting operations, financial reporting, and internal controls; ensure compliance with GAAP and applicable regulations, manage monthly, quarterly, and annual close processes and tax and regulatory filings; initiate/lead financial statement audits
• Partner with the CEO and leadership team to develop and refine the company’s financial strategy and long‑term operating plan; provide scenario modeling within budgets, forecasts, and long‑range planning models, and deliver capital allocation recommendations; support fundraising, investor relations, and board‑level financial reporting
• Implement and maintain innovative and scalable accounting and financial systems, processes and tools; oversee cash flow management, including tracking of R&D expenses, collaboration budgets and operational spend, and lead implementation of accounting and finance systems independent from the Flagship ecosystem
• Manage external vendors—auditors, accounting consultants, tax advisors, and payroll providers—holding them to scope, budget, and timeline
• Deploy AI accelerators across finance operations to improve speed, accuracy, and analytical capacity

• 15+ years of progressive finance and accounting experience, including senior leadership roles
• Proven track record in a private life sciences/biotech company through growth and successful inflection points
• Strong understanding of GAAP and biotech‑specific accounting issues, including R&D accruals, intercompany transactions, and collaboration accounting
• Experience in leading financial reporting, budgeting and long‑range planning processes
• Experience and comfort as an individual contributor as well as leading small teams, including external vendors
• Demonstrated ability to work independently in a fast‑paced, entrepreneurial environment
• CPA or MBA strongly preferred
• Experience supporting fundraising activities (venture capital, crossover, IPO readiness)
• Understanding of and interest in utilizing AI and automation for finance
• Familiarity with biopharma collaboration accounting and reporting as well as cost modeling for R&D programs

Expedition Medicines currently offers healthcare coverage, an annual incentive program, retirement benefits, and a broad range of other benefits.

Salary range: $275,000 - $330,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

If you have some of the experience listed above but not all, please apply anyway.