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Cambridge, MA Senior Manager, Fellowship and Early Origination

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Flagship Pioneering
Full Time position
Listed on 2026-03-01
Job specializations:
  • Healthcare
  • Management
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below
Position: Flagship Pioneering | Cambridge, MA Senior Manager, Fellowship and Early Origination

Senior Manager, Fellowship and Early Origination

Cambridge, MA USA

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

Role

Description:

Flagship Pioneering is seeking an AI-native, PhD-trained scientist who is eager to think programmatically about the early stages of Flagship’s novel company creation process, which we call Origination. Under the oversight of Flagship’s Sr. Director of Fellowship and Talent Development, the Sr. Manager, Fellowship and Early Origination will manage a suite of responsibilities across the full lifecycle of the Flagship Pioneering Fellowship, from recruitment and interviewing to the planning, development and organization of materials that ensure the ongoing success of this critical pipeline of talent and ideas.

The Sr. Manager will also employ rigorous evaluation and continuous quality improvement approaches to surface best practices from the Fellowship and institutionalize them across Flagship Labs. In addition to Fellowship responsibilities, the Sr. Director will become a key contributor to Flagship’s broader strategy to leverage AI and off-the-shelf productivity tools to build and maintain systems and ways of working that support scaling, collaboration and efficiency across Flagship Labs, all while maintaining our culture of innovation and entrepreneurialism.

Skills and Behaviors:

The Sr. Manager, Fellowship and Early Origination must be able to partner with the Sr. Director, work independently, and join cross‑functional teams to develop, implement, and assess multiple simultaneous projects of varying scope and duration. Success will require self‑motivation, independence, flexibility, effective communication, and attention to detail. We expect a strong candidate will have demonstrated these skills and behaviors through prior work managing scientific or academic programs or through experience at a startup, venture or consulting firm.

A track record of successfully completing projects across various domains is a must. Experience working directly with trainees and familiarity with the best practices of program evaluation will be helpful but are not required.

Core Duties

  • Support the Sr. Director, Fellowship and Talent Development in strategic and operational capacities across the full lifecycle of the Flagship Pioneering Fellowship, including recruitment, explorations, data stewardship, hiring decisions, and program evaluation
  • Serve as an independent liaison between the Sr. Director and Fellowship stakeholders across Flagship Labs
  • Collaborate with the Sr. Director and Flagship Labs leadership to build technical and operational solutions that maximize and streamline Flagship’s company creation pipeline
  • Ensure that timely and accurate data on Fellowship, explorations, and company starts are available to inform strategic decisions by Flagship Labs leadership
  • Collaborate with HR to support the professional development and productivity needs of Flagship Labs Associates

Requirements

  • An advanced degree (PhD or international equivalent) in any scientific or technical field
  • Project management experience beyond a laboratory environment, preferably in corporate, academic, or other professional settings
  • Experience using AI‑based approaches to solve…
Position Requirements
10+ Years work experience
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