Senior Associate Scientist, In Vitro Pharmacology

United States - Massachusetts - Cambridge

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.

To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.

Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.

Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting‑edge technologies to make a tangible impact on global health.

Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top‑tier medicines to patients worldwide.

• Design, develop and execute in vitro experiments to generate decision‑making data for portfolio programs.
• Act as an integral member of research project biology teams, recommending options for in vitro experimentation, generating high‑quality in vitro pharmacology data and reporting results and conclusions at project team meetings.
• Design, develop and execute in vitro experiments to assess the potency and efficacy of molecules.
• Utilize single and multicolor flow cytometry to assess affinity and potency of molecules.
• Perform single and multiplexed MSD/conventional ELISA experiments to quantify cellular cytokine release.
• Work with whole blood and perform isolation and differentiation of cell subsets.
• Independently perform data analysis and present results at project meetings.

• Bachelor’s degree in Immunology or Pharmacology.
• 3+ years of experience performing in vitro based experiments in a Pharma/Biotech lab environment.
• Previous experience generating and analyzing single and multicolor flow cytometry data.
• Experience with MSD & ELISA experimentation.
• Experience in plate‑based experimentation and serial dilutions of large and small molecules.
• Strong understanding of fundamental in vitro pharmacology parameters and how to design and execute plate‑based experiments to quantify them.
• Confidence in troubleshooting experimental/assay challenges.
• Good sterile techniques for culture and maintenance of primary and immortalized cell lines.
• Competent user of Excel, Graph Pad Prism and PowerPoint for data analysis and presentation of results.

• Prior experience in working with both large and small molecule therapeutic modalities.
• Experience in drug discovery processes.
• Excellent organizational and time management skills.

Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.

Adhere to safe laboratory work practices and procedures.

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting‑edge technologies to make a tangible impact on global health.

Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top‑tier medicines to patients worldwide.

• Work Location Assignment:
  On Premise
• Last Day to Apply:
  March 5, 2026

The annual base…