Global Medical Director

Key Responsibilities

• Provide strategic and scientific leadership to and define global Medical Affairs strategy for CNS early-stage clinical programs.
• Serve as a key member of the product development teams and meaningfully impact clinical development plans, study design, and data interpretation.
• Lead and execute global scientific engagement strategy and drive excellence in scientific engagement with all key stakeholders.
• Develop, initiate, and maintain strong relationships with international scientific leaders and key stakeholders to enhance awareness of Alnylam's early asset portfolio.
• Organize and manage global expert events (advisory boards, expert panels, symposia). Functions as the scientific medical expert internally and externally with national and international stakeholders.
• Serve as a collaborator and key stakeholder in global clinical operations, global commercial development, global market access, global clinical R&D, global pharmacovigilance, and the promotion review committee (PRC) on medical aspects of the company's products.
• Provide strategic medical insights into R&D and commercialization strategies including profiling patient pathways, mapping the treatment landscape, and understanding prescriber patterns and dynamics.
• Serve as the Medical Affairs lead for strategic partnerships:
  • Partner with Value & Evidence Strategy team to develop and execute against integrated evidence generation plans
  • Partner with the Medical Communications team to ensure the development of global communication, strategy, and execution of timely and high-quality communication of scientific data (publication and medical congress)
  • Partner with Medical Training team to develop and deliver high quality scientific and skill-based training to medical team across regions
  • Partner with Omnichannel team to develop a strong Omnichannel prelaunch strategy for successful commercial launch.
• Liaise with global and regional Medical Affairs to ensure medical insights from all key markets are integrated into and inform product development.
• Oversee development and execution of comprehensive integrated evidence plans (IEP) s ensuring high-quality publications from all types of evidence throughout development, launch, and in-market for all Alnylam pipeline and inline products.
• Provide medical expertise and input into TA strategies ensuring close collaboration with R&D to deliver data and a label to support the Target Product Profile (TPP) s and reflect the value required to enable speedy patient access.

• MD, PhD, Pharm D or equivalent ex-US medical degree
• 5+ years of demonstrated high-level professional knowledge and skills in Medical Affairs and R&D, especially familiarity with early clinical development, in the pharmaceutical or biotech industry.
• Deep therapeutic area knowledge and experience in Neurological Diseases.
• Extensive knowledge of the latest regulatory, policy, and technology developments preferred.
• Experience in global scientific engagement strategy including scientific congresses, external experts and panels, symposia, etc., preferred.
• Influential matrix leader who builds relationships across stakeholder types
• Leadership presence with the ability to communicate complex data persuasively and relate study results and knowledge of therapeutic area to industry-specific applications Experience with RWE, diagnostics, translational work, and digital innovations.
• Demonstrated expertise in informing R&D and commercialization strategies including patient pathways and mapping treatment landscape.
• Preferred experience in working with Clinical development team and help shape CDP, data interpretation and dissemination.
• Experience supporting due diligence for Business Development and serving as a medical expert for integrated asset planning, and building medical assessment framework.
• High degree of professionalism, maturity, and confidentiality.
• Strong written and verbal communication skills as well as strong leadership and interpersonal skills.
• Demonstrated reputation as a well-respected, dynamic team player-coach.
• Ability to deliver on company global program goals and objectives as they pertain to Medical Affairs.
• Ability to influence…