Director, Translational Medicine, Imaging

Director of Imaging and Biomarkers, Translational Medicine

Blue Rock Therapeutics, a leading engineered cell therapy company, is pioneering a new generation of cellular medicines. Our mission is to harness pluripotent stem cell technology and gene editing to deliver authentic, functional cell therapies that address the root causes of disease and offer hope to millions of patients worldwide.

The Director of Imaging and Biomarkers, Translational Medicine, will be expected to take on a highly visible role with internal and external stakeholders through the management of the imaging protocols and biomarkers leveraged in Blue Rock's clinical development programs. The Director of Imaging and Biomarkers will leverage their expertise in CNS, ophthalmic and inflammation imaging to advance the company's development pipeline by working closely with program leads and other subject matter experts.

The position will be based in Cambridge, Massachusetts.

Responsibilities:

• Develop translational strategies designed to support clinical development plans, the regulatory path, and product commercialization.
• Lead the development and implementation of translational imaging strategies in support of clinical proof-of-mechanism, patient stratification, dose selection.
• Serve as the neuroimaging lead on cross-functional program teams.
• Partner with Research to discover and characterize novel imaging biomarkers in preclinical studies.
• Develop imaging methods and analytically validate imaging tools for clinical use.
• Implement clinical biomarkers and ensure biomarker-driven decision-making across all phases of drug development.
• Lead cross-functional imaging governance (e.g., Imaging Steering Committee) advancing the use of imaging biomarkers to enable demonstration of disease-modifying effects.
• Deliver subject matter expertise with respect to clinically advanced techniques in MRI, PET, SPECT, HRCT and other modalities as needed.
• Oversee CRO vendor/partners ensuring that they optimally execute clinical and preclinical imaging projects in the US, Canada, and other regions of interest.
• Provide support for the Business Development organizations as needed on diligence efforts.

Minimum Requirements:

• PhD, MD, PharmD, or equivalent degree in Neuroscience, Biomedical Imaging, Radiology, or related discipline.
• 6+ years of industry experience in translational medicine, imaging sciences, or clinical development
• Deep expertise in clinical and translational neuroimaging, including MRI and PET methodologies
• Must have direct experience managing imaging protocols in the conduct of clinical trials (endpoints, inter-site harmonization, imaging core lab oversight, etc.).
• Specific experience with imaging endpoints for early-stage clinical development in CNS, ophthalmic and inflammatory diseases is desired.

The estimated compensation range for this position is $ - $ per year.

Equal Opportunity Workplace:
At Blue Rock, we welcome and support differences and diversity and we are proud to be an equal opportunity workplace. Please let us know if you require disability-related accommodation or other grounds protected by human rights legislation during the recruitment process so that we can work with you to meet your needs.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.