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Senior Manager, HEOR & Evidence Strategy

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Stratacuity: Proven Scientific Placement
Full Time position
Listed on 2026-09-13
Job specializations:
  • Healthcare
    Clinical Research
  • Research/Development
    Clinical Research
Salary/Wage Range or Industry Benchmark: 150000 - 190000 USD Yearly USD 150000.00 190000.00 YEAR
Job Description & How to Apply Below

Senior Manager, HEOR & Evidence Strategy

Join an innovative biotechnology organization advancing transformative therapies for patients with serious and rare diseases. We are seeking a Senior Manager, HEOR & Evidence Strategy to support evidence generation initiatives that demonstrate the clinical, economic, and patient-centered value of novel therapies and help ensure optimal patient access globally.

Reporting to the Director of HEOR & Evidence Strategy, this individual will partner cross-functionally with Clinical Development, Medical Affairs, Market Access, Biostatistics, Regulatory Affairs, and Commercial teams to develop and execute evidence strategies across the product lifecycle.

Key Responsibilities
  • Lead and support the development of HEOR and evidence generation strategies for pipeline and commercial-stage products.
  • Design and manage primary and secondary research initiatives, including retrospective database studies, systematic literature reviews, health technology assessment (HTA) evaluations, and outcomes research.
  • Contribute to integrated evidence generation plans (IEGPs), value propositions, and clinical outcomes assessment strategies.
  • Support the creation of market access deliverables including value narratives, global value dossiers, economic models, and meta-analyses.
  • Collaborate with development teams to incorporate payer, reimbursement, and health economic considerations into clinical development programs.
  • Develop long-term evidence strategies that support reimbursement, market access, and patient adoption.
  • Conduct HEOR analyses to inform portfolio and asset-level strategic decision-making.
  • Manage external vendors, consultants, and research organizations to deliver evidence generation projects on time and within budget.
  • Support annual planning, budgeting, and resource allocation activities.
Qualifications
Education
  • Master's degree in Health Economics, Epidemiology, Public Health, Data Science, Life Sciences, or a related field required.
  • Advanced degree (PharmD, PhD, MD, MBA, or equivalent) preferred.
Experience
  • 3-5 years of experience in Health Economics & Outcomes Research (HEOR), evidence generation, biopharmaceuticals, healthcare consulting, or life sciences.
  • Experience supporting innovative therapeutic modalities, rare diseases, or specialty medicine programs preferred.
  • Experience in immunology, neurology, cardiology, or related therapeutic areas is a plus.
Desired Skills
  • Strong understanding of HEOR methodologies and evidence generation frameworks.
  • Knowledge of payer systems, reimbursement models, and value assessment frameworks.
  • Experience supporting market access initiatives in pre-launch or launch environments is preferred.
  • Ability to manage multiple projects and stakeholders while balancing timelines and budgets.
  • Excellent analytical, strategic thinking, communication, and presentation skills.
  • Proven ability to work effectively within cross-functional and matrixed organizations.
  • Self-motivated, organized, and adaptable with a strong sense of accountability.
  • Comfortable operating in a fast-paced, evolving environment with shifting priorities.
  • Hybrid work arrangement preferred, with periodic on-site collaboration.
Position Requirements
10+ Years work experience
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