IT Manager

100 Cambridge park Dr, Cambridge, MA 02140, USA

Posted Thursday, February 12, 2026 at 11:00 AM

LOCATION:

Cambridge, MA (hybrid)

This position reports to our global HQ in Cambridge, MA

TriNetX was founded on the idea that incorporating real‑world data results in better clinical trial design, improves the site selection and patient recruitment process and generates real‑world evidence (RWE) to advance the collective understanding of human health. TriNetX collaborates with the majority of industry leaders, including 13 of the top 15 pharmaceutical companies, and is powered by an impressive network of 170 healthcare organizations across 30 countries.

As a result of its reach and rapidly expanding network, TriNetX has become the market leader in protocol design, feasibility, and site selection. Researchers have leveraged the TriNetX network to analyze over 39,000 protocols, presented over 10,000 clinical trial opportunities to its healthcare members, and reduced site identification time in clinical trials by 50%.

Currently, TriNetX healthcare organization members contribute access to a patient population of 400 million, representing over 40 billion clinical observations. TriNetX has a worldwide presence, with our global headquarters located in Cambridge, Massachusetts and EU offices in Ghent, Belgium;
Freiburg, Germany; and Basel, Switzerland – as well as offices in London, Madrid, Sao Paulo, and Singapore. As a result, TriNetX is one of the fastest‑growing, privately held companies in the life sciences industry.

TriNetX is the global health research network that optimizes clinical research and enables discoveries through the creation of real‑world evidence. TriNetX combines real‑time access to longitudinal clinical data with state‑of‑the‑art analytics to answer complex research questions at the speed of thought. Each member of our community shares in the consolidated value of our global, federated health research network that connects clinical researchers to the patient populations which they are attempting to study.

The IT Manager will oversee the organization’s information technology operations, ensuring the availability, performance, and security of all systems and infrastructure. This role combines strategic leadership with hands‑on oversight of the IT support function, ensuring efficient delivery of technical services and outstanding end‑user support. The ideal candidate is both a strong technical expert and an effective people leader who can drive continuous improvement across IT operations.

• Lead the planning, implementation, and maintenance of IT systems, network infrastructure and cloud services.
• Evaluate and implement new technologies to support organizational goals.
• Collaborate with leadership to define IT strategies aligned with business objectives.
• Develop, maintain, and execute the overall IT roadmap , ensuring alignment with organizational goals, technology lifecycle planning, and future growth.
• Oversee IT asset management, including procurement, lifecycle management, and inventory control.
• Mentor and develop IT staff through training, coaching, and performance management.
• Delegate tasks, manage schedules, and ensure adequate support coverage.
• Ensure timely resolution of user requests, incidents, and escalations with a focus on customer service.
• Develop and enforce IT support processes, SLAs, and escalation procedures.
• Implement and maintain workflow automation within ITSM systems such as Jira Service Management, Serive Now or similar platforms to streamline ticket routing, approvals, asset tracking, and reporting.
• Analyze recurring issues to identify root causes and implement long‑term solutions.
• Maintain documentation, knowledge bases, and user guides to improve support efficiency.

• Bachelor’s degree in Information Technology, Computer Science, or related field (or equivalent experience).
• 5+ years of progressive experience in IT operations, including leadership of support teams.
• Strong knowledge of networking, cloud platforms, cybersecurity, and enterprise systems.
• Hands‑on…