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Senior Engineer, Clinical Supply Chain; SAP ICSM

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Moderna Therapeutics
Full Time position
Listed on 2026-02-20
Job specializations:
  • IT/Tech
    Cybersecurity, Systems Engineer, Data Security
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Senior Engineer, Clinical Supply Chain (SAP ICSM)
*
* The Role:

** Moderna is seeking a candidate to design, build, and support SAP ICSM capabilities that enable reliable, compliant clinical trial supply planning and operations.

This role is a hands-on SAP engineer who will configure and extend ICSM, integrate ICSM’s cloud components on SAP BTP with SAP S/4

HANA extensions, and partner with Clinical Supply Chain, Clinical Operations, Quality, and external partners (CMOs/3PLs) to deliver validated solutions in a regulated environment.
** Here’s What You’ll Do
*** Configure and support SAP ICSM modules and processes (Study Management; Medication List, Planning & Forecasting; Manufacturing & Packaging; Distribution) to enable clinical supply execution and visibility.
* Partner with business stakeholders to translate protocol/study requirements into system design (e.g., study parameters, demand drivers, supply strategy, labeling/packaging needs, depot/site distribution workflows).
* Implement and maintain integrations between ICSM and the clinical supply ecosystem, including CTMS and IRT systems (enrollment/dispensing signals, randomization/blinding interfaces), as well as external stakeholders such as CMOs and 3PLs.
* Build and support the ICSM hybrid architecture: BTP-to-S/4 communication patterns (e.g., cloud connectivity, event-driven synchronization, API-based data exchange) and operational processes executed in SAP S/4

HANA.
* Contribute to traceability and logistics enablement where applicable (e.g., integration touchpoints with SAP Advanced Track and Trace for Pharmaceuticals and/or GS1-based interfaces with partners).
* Lead technical delivery across the lifecycle: requirements, functional/technical design, build/configuration, test strategy and execution (unit/SIT/UAT), cutover, and hypercare.
* Operate within a validated (GxP) landscape: produce required documentation, support validation testing, manage changes through controlled processes, and ensure audit readiness.
* Provide L2/L3 support for ICSM, including incident triage, defect resolution, performance troubleshooting, and continuous improvement (enhancements, automation, monitoring).
* Collaborate closely with SAP platform, integration, and security teams to ensure solutions meet Moderna standards for identity/access, data protection, and operational resilience.
** Here’s What You’ll Need (Basic Qualifications)
*** Bachelor’s degree in computer science, Engineering, Information Systems, Supply Chain, or a related field (or equivalent experience).
* 8+ years of SAP engineering experience, including end-to-end implementation and/or support of SAP solutions in regulated enterprise environments.
* Experience implementing or supporting SAP ICSM (preferred) or closely related life-sciences supply chain solutions, with strong understanding of clinical supply concepts and workflows.
* Solid understanding of the integration of SAP ICSM with SAP IBP, SAP S/4

HANA, SAP MDG and SAP EWM (embedded)
* Hands-on experience with SAP S/4

HANA logistics/manufacturing processes relevant to clinical supply execution (e.g., medication list, materials management, production, quality, warehousing/logistics).
* Experience operating in GxP/CSV contexts (documentation, testing evidence, change control, audit support).
* Strong communication and stakeholder management skills; ability to work cross-functionally with Clinical Supply Chain, Clinical Operations, Quality, and external partner
** Here’s

What You’ll Bring to the Table (Preferred Qualifications)
*** Experience with SAP BTP services used in ICSM architectures (connectivity, integration, eventing) and Fiori-based application enablement.
* Experience integrating with CTMS and IRT vendors and understanding of signals like enrollment, visits, dispensing, returns, and destruction flows.
* Familiarity with traceability/serialization concepts and/or Medication List
* Experience with data and analytics enablement for clinical supply visibility (KPIs, dashboards, exception management)
** Pay & Benefits
**** At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at…
Position Requirements
10+ Years work experience
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