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Senior Systems Engineer, Digital Research and Technical Development

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Moderna Therapeutics
Full Time position
Listed on 2026-03-12
Job specializations:
  • IT/Tech
    Systems Engineer, Cybersecurity, Cloud Computing, IT Support
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Senior Systems Engineer, Digital for Research and Technical Development
** The Role
** Moderna is seeking an individual responsible for lifecycle management, optimization, and continuous improvement of laboratory digital systems across our Research and Technical Development organization.

This role supports and maintains a diverse ecosystem of standalone laboratory systems and enterprise platforms while remaining technology-agnostic and solution-oriented.

The ideal candidate combines strong engineering discipline with deep laboratory domain knowledge and a systems-thinking mindset. They will ensure system reliability, compliance, scalability, and interoperability across platforms in support of R&TD laboratories.
** Here's What You’ll Do
*** System Ownership & Lifecycle Management:
Serve as a technical owner for digital laboratory systems across multiple platforms
* Manage lifecycle of laboratory applications and digital platforms, including configuration, upgrades, patching, validation, and retirement.
* Manage lifecycle of laboratory instrument controller systems and associated client hardware, including OS upgrades, vendor coordination, hardware refresh, and cybersecurity hardening.
* Ensure systems meet performance, availability, security, and compliance requirements.
* Define and maintain backup, disaster recovery, and business continuity strategies for laboratory systems.
* Platform-Agnostic Engineering:
Design and implement solutions independent of specific vendors or technologies.
* Evaluate and integrate new lab systems and digital tools using standardized architectural principles and best practices.
* Develop automation and standardized deployment patterns to improve scalability and reduce manual configuration across laboratory systems.
* Support hybrid architectures spanning instrument-connected edge systems and cloud-based enterprise platforms.
* Incident & Change Management:
Track incidents and service requests; develop and maintain knowledge base documentation.
* Provide advanced technical support and perform root cause analysis for complex system issues.
* Support changing management activities in alignment with IT governance standards.
* Integration & Data Integrity:
Design, implement, and maintain integrations between lab systems and enterprise platforms (e.g., ELN, LIMS, data lakes, analytics platforms).
* Ensure data integrity, traceability, and secure data flows across systems.
* Support data governance initiatives and master data harmonization efforts.
* Continuous Improvement & Strategy:
Identify opportunities to streamline laboratory workflows and enhance user experience.
* Contribute to digital laboratory strategy and roadmap development.
* Evaluate emerging technologies and recommend scalable, future-ready solutions.

* Cross-Functional Collaboration:

Serve as a trusted technical advisor to laboratory and digital stakeholders, translating scientific workflows and business requirements into scalable engineering solutions while clearly articulating technical trade-offs, risks, and constraints.
* Partner with laboratory scientists, lab administrators, IT infrastructure, cybersecurity teams, and external vendors to deliver secure, compliant, and reliable laboratory systems.
* Partner with Cybersecurity to implement secure architectures for laboratory networks and deployments.
* Mentor and provide technical guidance to junior engineers.
** What You’ll Need (Basic Qualifications)
*** Bachelor’s degree in Biomedical Engineering, Computer Engineering, Computer Science, or related field, or equivalent experience.
* 5–8 years of hands-on experience supporting laboratory equipment controller PCs and/or enterprise platforms within pharmaceutical, biotechnology, or medical device environments.
* Demonstrated experience supporting instrument-connected systems where hardware interfaces, firmware versions, vendor drivers, and acquisition workflows must be carefully managed to avoid operational disruption.
* Strong expertise in troubleshooting laboratory instrument communication across Windows-based, Linux-based, and proprietary operating systems.
* Proven experience working with laboratory applications (web-based and client-server) and their underlying database architecture.
*…
Position Requirements
10+ Years work experience
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