Hematology RWE Science & Epidemiology Manager

This role will be responsible for intaking franchise and asset integrated evidence plans and tactics, then delivering high quality RWE, RW insights or other patient-centric evidence for prioritized projects to fully the tactic or strategic pillar, as directed by their supervisor in accordance with the RWE Strategic Planning team based on cross-functional partners’ strategic priorities.

The remit spans from global and prioritized international markets, where the evidence will be used to respond to regulatory commitments / requests, HTA/government entity needs and key projects that have been prioritized in a managed work queue by the global medical strategy committee. The role is highly technical and will execute hands-on evidence generation via a combinatorial approach of cutting edge retrospective data analyses, site-based evaluations (e.g., Phase IV observational effectiveness studies, burden of illness, transmission, pathogenesis, risk factors for illness, determinants of product effectiveness and other studies), application of novel methods and technologies, and supplementation of interventional trials where appropriate with RWE through hybrid trial designs and tokenization.

This will represent significant learning experience and growth for the successful candidate. The Platform will insource this work to the fullest possible extent, so prospective candidates who have outsourced work to contract research organizations need not apply.

Within the RWE Platform, a dedicated team of RWE Scientists will support the TA teams within the Primary Care category, reporting to the Hematology RWE Science & Epidemiology Team Lead. Leveraging their understanding of how RWE can support the entire lifecycle from molecule to marketplace, the RWE Science & Epidemiology Manager will deliver timely real world insights (RWI) by understanding cross-functional pipeline / asset team’s strategic objectives and timelines, collaborate with the team and RWE Biostatistics & other relevant colleagues to generate RWE, and direct creation of easy-to-understand summary reports as directed by their supervisor.

They will receive mentorship to help build or advance a nuanced understanding of real world data, what fit-for-purpose data needs are for different applications, and which sources are most appropriate for completing objectives, partnering closely with the Platforms & Partnerships and Patient Advocacy & External Partnerships teams. The RWE Scientist will ensure the development of consistent business rules and standards, versioning rules as care pathways evolve.

ROLE RESPONSIBILITIES

• As instructed, leads RWI for feasibility assessments, go/no-go decisions, co-design and create dashboards to inform cross-functional teams’ hypothesis generation, generate timely and detailed insights.

• Collaborates with team members to build strong internal and external partnerships and act as a junior subject matter expert by providing expert consultations on all aspects of RWD studies and analyses, including feasibility assessment, objectives, study design, data source identification, protocol development, statistical analyses, and table shells.

• Conduct and oversee the execution of rapid RWD-based queries and studies and effectively communicate the findings and study results to internal stakeholders using tables, visualizations, short reports, and slide decks.

• Apply quality standards and processes to manage quality, consistency, usability, security, and availability of data throughout the data lifecycle; stay up to date on RWD/E best practices.

• Participates actively on internal cross-functional teams, RWE Biostatistics, and other colleagues to create high-quality RWE from rigorously designed protocols.

• Help to collaboratively write high-quality methods, innovative approaches, protocols, and designs.

• Generate RWE through collaborations with the pipeline/asset teams (e.g., pipeline teams, Global Product Development franchise/asset teams, BU Medical affairs, HEOR, Commercial and other functions), RWE Biostatistics, and other functions as directed.

Document all requests and track progress toward project completion, create and measure quarterly ROI…