Head of Chemistry, Drug Design, Cambridge, MA

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we're building today. It starts with the culture at this company. It starts with you.

About Iso

Isomorphic Labs (Iso Labs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning Alpha Fold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world's most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we're getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

About the Medicinal Drug Design Team

We are building a dynamic team of Medicinal Chemists in Cambridge, MA, to transform how drugs are designed. By partnering deeply with our AI/ML colleagues, we are doing more than just leveraging the Isomorphic Labs Drug Design Engine - we are actively shaping it. We use our domain expertise to challenge and refine our algorithms, creating a powerful symbiotic relationship that drives our internal and collaborative portfolios.

Our team work closely together in a supportive environment, where everyone is valued for their medicinal chemistry expertise and experience they bring to the group. We have a strong growth mindset and prioritise continued development and learning.

Your impact

As part of our expansion to Cambridge, MA, we are seeking an experienced and strategic Head of Chemistry to join our foundational Drug Design team. This is a pivotal role for a motivated scientific leader who is eager to shape the future of drug discovery at the intersection of medicinal chemistry and artificial intelligence.

You will provide scientific leadership and strategic direction for the Medicinal Chemistry team, responsible for delivery and guidance of projects to clinical candidate nomination. Additionally, you will oversee and mentor a team of talented Medicinal Chemists, fostering their scientific growth and career development. Working alongside world-leading AI/ML Scientists, you will play a critical role in driving project success, enhancing our AI platform through expert feedback, and building a high-performing Chemistry team.

Critical to this role will be the ability to build highly effective and efficient connectivity with Computational Drug Design, Biology and Pre-Clinical Development teams to accelerate pace to the clinic. If you are a skilled Medicinal Chemist with leadership experience and a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.

What you will do

* Apply your knowledge and track record of modern drug design & discovery principles to deliver our Drug Design portfolio, either directly as a Chemistry or Project Lead, or indirectly, strategically guiding other Chemistry Leads.

* Provide direct line…