Senior Manager, Research Equipment

Senior Manager, Research Equipment

Why Join Us?

As a member of the Parabilis Medicines team, you will be a part of an organization dedicated to creating extraordinary medicines for diseases with urgent unmet needs, harnessing our proprietary peptide platform to transform treatment possibilities for patients. Parabilis is a clinical-stage biopharmaceutical company dedicated to unlocking high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides - Helicons™ - capable of modulating intracellular proteins that are inaccessible to traditional drug modalities.

Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors.

In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered "undruggable" despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution.

What's the opportunity?

The Senior Manager, Research Equipment is responsible for enabling Parabilis' cutting-edge research by ensuring laboratory equipment is strategically selected, optimally configured, highly reliable, and continuously improving. This role owns the full lifecycle of research instrumentation and partners closely with Research, Finance, Facilities, IT, Quality, and external vendors to minimize downtime, enable automation, and support scalable, reproducible science.

This position requires deep and broad technical expertise across research equipment platforms, strong operational rigor, and the ability to integrate automation, data, and AI-driven approaches into lab operations. The Senior Manager, Research Equipment plays a critical role in aligning equipment strategy with scientific roadmaps, growth plans, and financial and regulatory requirements.

Key Responsibilities

Equipment Lifecycle & Operational Excellence

• Own and lead the full lifecycle of research equipment - from needs assessment and acquisition through installation, operation, hands-on maintenance, and retirement, ensuring high availability, performance, and alignment with evolving research needs.
• Operate as the accountable leader for day-to-day equipment performance, including personally driving troubleshooting, repairs, and preventive maintenance programs to minimize downtime and enable continuous research operations.
• Lead from the front on installation, qualification, validation, and calibration of laboratory instruments in coordination with vendors, Facilities, IT, and internal stakeholders, applying continuous improvement principles.
• Maintain comprehensive, audit-ready documentation, including equipment inventories, maintenance logs, calibration records, service contracts, and validation documentation, in alignment with internal policies and applicable regulatory expectations.
• Establish, measure, and maintain key performance indicators (KPIs) for equipment reliability, utilization, and downtime. Use data to proactively identify upcoming issues and drive improvements.

Training, Partnership & Vendor Management

• Serve as the primary in-lab point of contact for equipment-related issues across research labs. Build credibility across teams through responsiveness, technical depth, and ownership.
• In partnership with power users, develop and deliver technical training to ensure safe, effective, and compliant use of high use laboratory instruments.
• Build strong…