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Associate Director, Clinical Program Management, Cambridge, MA

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Isomorphic Labs
Full Time position
Listed on 2026-08-26
Job specializations:
  • IT/Tech
    AI Engineer (Applied/Software), Data Science Manager, Data Analyst
Salary/Wage Range or Industry Benchmark: 140000 - 210000 USD Yearly USD 140000.00 210000.00 YEAR
Job Description & How to Apply Below

Associate Director, Clinical Program Management, Cambridge, MA

Cambridge, MA

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.

About Iso

Isomorphic Labs (Iso Labs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning Alpha Fold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

Your impact

The experienced Associate Director of Clinical Program Management will help to lead the transition of our internal programs from pre-IND to clinical trial execution. Reporting to the Program Lead, this critical role will work with the cross-functional global team to drive clinical trial execution, managing timelines, risks, budgets and vendor partnerships. They will leverage AI and emerging technologies to ensure efficient outcomes with a high probability of success.

What you will do
  • Project planning and execution: Develop and own integrated project plans that track operational strategy, timelines, risks and dependencies across work streams to ensure alignment between clinical objectives and company goals.
  • Cross-functional leadership and communication: Act as the central point of contact ensuring high performance and alignment among the cross-functional clinical trial team.
  • Lead project team meetings ensuring effective information sharing, decision making and documentation.
  • Collaborate with preclinical program managers as well as AI/ML and data science teams to identify and implement new solutions to increase speed, scale and probability of success.
  • External Partnerships: Oversee and manage a network of external vendors, CROs, partners and collaborators including budgets, timelines and key deliverables.
  • Stakeholder Management: Provide regular updates to leadership and key stakeholders on clinical study execution and portfolio management.
  • Proactively and in real-time help teams to problem solve and identify issues that impact key deliverables, timelines and budgets.
Skills and qualifications
  • You must have a proven track record of managing a clinical program from IND through late stage clinical development, within expected timelines and budgets.
  • Experience working cross functionally with key stakeholders internally as well as external vendors and collaborators. Excellence in building relationships in both settings.
  • Highly organized with experienced managing large budgets and complex interdependent timelines using project management tools.
  • Strong sense of urgency and accountability to operate in a fast-paced environment.
  • Flexibility to adapt to changing…
Position Requirements
10+ Years work experience
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