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Principal DevOps Engineer, AI Inference

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Lila Sciences
Full Time position
Listed on 2026-09-01
Job specializations:
  • IT/Tech
    Systems Engineer, Cloud Computing: Infrastructure & Operations, SRE/Site Reliability, AI Engineer (Applied/Software)
Salary/Wage Range or Industry Benchmark: 192000 - 272000 USD Yearly USD 192000.00 272000.00 YEAR
Job Description & How to Apply Below
Position: Staff/Principal DevOps Engineer, AI Inference

Staff/Principal Dev Ops Engineer, AI Inference

Cambridge, MA USA

The Staff/Principal Dev Ops Engineer - AI Inference will drive the design, implementation, and optimization of infrastructure purpose-built for serving machine learning models s role bridges platform engineering, site reliability, and ML infrastructure, building the systems that power low-latency, high-throughput inference across GPU clusters and cloud accelerators. You will collaborate with ML engineers, research scientists, and software engineers to build inference platforms that serve models reliably to production users while maximizing compute efficiency.

What

You'll Be Building
  • GPU/accelerator infrastructure on Kubernetes: scheduling, resource isolation, multi-tenant GPU sharing, device plugins, and topology-aware placement for inference workloads
  • Model serving platforms using frameworks such as vLLM, Triton Inference Server, TGI, or custom serving stacks with optimized batching, caching, and request routing
  • Intelligent request routing and load balancing across heterogeneous accelerator fleets (NVIDIA GPUs, AWS Inferentia/Trainium) to maximize utilization and minimize latency
  • Autoscaling systems that dynamically match inference compute supply with demand across production, research, and experimental workloads
  • Production-grade deployment pipelines for ML models: canary rollouts, A/B testing, model versioning, and safe rollback across multi-region deployments
  • Infrastructure-as-code with Terraform and Helm for GPU-accelerated EKS clusters, including node pools, spot/on-demand strategies, and accelerator-specific networking
  • Observability and performance optimization: GPU utilization monitoring, inference latency profiling, token throughput dashboards, and SLO/SLI tracking for model endpoints
  • CI/CD pipelines for model artifacts: container image builds with CUDA/driver dependencies, model registry integration, and automated inference benchmarking in CI
  • AWS cloud infrastructure for ML: EKS with GPU node groups, EC2 accelerated instances (P4/P5, Inf2, Trn1), S3 model storage, EFA/high-bandwidth networking, and IAM least privilege
  • Cost optimization and capacity planning: right-sizing accelerator instances, spot instance strategies for inference, and fleet-wide efficiency reporting
What You'll Need to Succeed
  • Expertise in Dev Ops, SRE, or Platform Engineering with significant experience operating GPU/accelerator infrastructure at scale
  • Deep experience with Kubernetes for ML workloads: GPU scheduling, resource quotas, node affinity, and accelerator device management
  • Strong proficiency deploying to AWS using infrastructure-as-code (Terraform, Helm) with hands-on experience managing GPU-based compute (EKS, EC2 P-series/Inf/Trn instances)
  • Experience with model serving infrastructure: inference servers, request batching, KV-cache optimization, or LLM serving frameworks
  • Strong understanding of networking for distributed inference: high-bandwidth interconnects, NCCL, VPC/Private Link, and load balancing at L4/L7
  • Strong proficiency in Python for automation, tooling, and integration with ML frameworks
Bonus Points For
  • Experience with LLM inference optimization: continuous batching, speculative decoding, quantization (GPTQ, AWQ, FP8), tensor parallelism, and pipeline parallelism
  • Hands-on experience with multiple accelerator families (NVIDIA A100/H100, AWS Inferentia2, Trainium, AMD MI300X) and maintaining hardware-agnostic serving infrastructure
  • Multi-region deployment experience with geographic routing and failover for latency-sensitive inference endpoints
  • Proficiency in Rust or Go for performance-critical infrastructure components
  • SRE practices for ML systems: chaos engineering on GPU workloads, incident management, capacity modeling for bursty inference traffic
  • Experience with model registries, artifact versioning, and ML supply chain security
  • Observability platform expertise: building custom metrics for token-level throughput, time-to-first-token, and per-request GPU memory profiling
  • Prior startup/high-growth experience balancing velocity with reliability in rapidly scaling AI systems
Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits.

Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits.

Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.

-based positions; international salaries are set to local market.

Expected Base Salary Range

$192,000 - $272,000 USD

About LILA

Lila Sciences is building Scientific…

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