Senior Manager, Solutions Architect

About Parabilis Medicines

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable. The company has pioneered a new class of alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines. The company's lead investigational medicine, zolucatetide, is the first and only direct inhibitor of the β-catenin:

TCF interaction, a central node in the Wnt/β-catenin pathway that has eluded drug developers for decades. Zolucatetide is being evaluated in the clinic across multiple Wnt/β-catenin-driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications. Beyond zolucatetide, Parabilis is advancing additional Helicon-based programs focused on other challenging targets where we believe our medicines could have life-altering impact.

For more information,  or follow us on Linked In.

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable. The company has pioneered a new class of alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines. The company's lead investigational medicine, zolucatetide, is the first and only direct inhibitor of the β-catenin:

TCF interaction, a central node in the Wnt/β-catenin pathway that has eluded drug developers for decades. Zolucatetide is being evaluated in the clinic across multiple Wnt/β-catenin-driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications. Beyond zolucatetide, Parabilis is advancing additional Helicon-based programs focused on other challenging targets where we believe our medicines could have life-altering impact.

For more information,  or follow us on Linked In.

Parabilis is scaling toward a commercial future, and the systems our teams rely on have too often grown one step at a time rather than being designed as coherent wholes. The Enterprise Solutions Architect exists to change that. This is a senior, cross-functional design and delivery role that partners with business teams, internal technology functions, and external vendors to evaluate, design, and deploy streamlined, well-architected workflows and the data foundations beneath them.

You bring enough technical depth to make the design calls yourself, and enough project and stakeholder leadership to carry them through to a working system in production.

This role holds design authority for the systems and workflows it builds, and leads the projects that deliver them - scope, sequencing, timeline, risk, and vendor execution. It does not direct how any business team performs its work. Instead, it partners with those teams to translate how they need to work into cohesive, maintainable systems that let them add value rather than work around disconnected point solutions.

You will be a force multiplier: the person who sees the whole board when everyone else sees their own square.

• Owns (design and delivery authority): end-to-end architecture, workflow design, and data models for the systems you build, plus the delivery plan behind them - scope, milestones, dependencies, risks, and vendor performance. These are yours to decide and drive, with the backing of the Sr. Director of IT.
• Partners on: requirements with…