Manager, Commercial Supply Chain

Manager, Commercial Supply Chain

Agios Pharmaceuticals is searching for a dynamic Manager, Commercial Supply Chain to join our growing team. Agios outsources all cGMP manufacturing operations to third‑party CMOs across API, bulk drug product, and final packaged goods. The selected individual will have full exposure across the different areas of the commercial supply chain and across early clinical to new commercial product launches. The individual will also support our growing global footprint as our distribution expands to other markets outside of the US, which will also involve responsibilities for life‑cycle management.

Additionally, this role will be responsible for supporting the commercial supply chain department across systems, planning and operations.

Agios is committed to an inclusive culture, collaboration and innovation. Our team’s proven track record of executional excellence and depth of expertise enables us to develop innovative medicines that reflect the priorities of rare disease communities.

• As a member of cross‑functional teams that include CMC, QA, and regulatory, execute activities for the Commercial Supply Chain Operations team on assigned projects.
• Oversee timelines for both internal activities and external production activities at Contract Manufacturing Organizations (CMOs) to ensure continuous supply of commercial and clinical materials through the supply chain.
• Ensure accurate inventory in Agios’ inventory management system, including production, data entry and reporting.
• Support commercial artwork changes for existing commercial products and collaborate with the artwork team to develop new artwork for new product or market launches.
• Own change controls and support deviation investigations and other quality events.
• Collaborate with Finance and Cost‑Accounting team to ensure proper inventory accounting and financial reporting.
• Issue purchase orders and track invoices to maintain project budgets.
• Maintain and communicate production schedules at all inventory levels.
• Oversee and maintain production key performance indicators for each supplier.
• Manage department projects, including product launch activities, to ensure that action items are tracked against a project plan.
• Support supply planning for both clinical and commercial supply chain needs as required.

• Bachelor’s degree in Engineering, Business, Supply Chain/Material Management, or a life science field.
• 5+ years of experience in supply chain or GMP manufacturing environment.
• Experience using ERP/SAP.
• Ability to travel 25% for production or supplier oversight.
• Detail‑focused with the ability to influence suppliers and projects with minimal oversight, yet work collaboratively within a team environment.

• Experience working with CMO partners.
• Experience with new product launches.
• Experience with continuous manufacturing.
• Experience with EU/GCC regional requirements.

Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply.

Location agnostic:
This role can be remote in the U.S. or hybrid at our Cambridge Headquarters, with a hybrid schedule generally less than three days per week onsite. Remote employees work entirely from home, except for company‑sponsored events or meetings. Travel may be required for certain company events as commensurate to the job description.

• Deliberate Development. Your professional growth is one of our top priorities.
• Flexibility. We embrace individual needs, different perspectives, work styles, health and wellness approaches, and caring for families, enabling everyone to perform at their best.
• Premium benefits package. We invest in the health, wellbeing, and security of our people with a well‑rounded and flexible benefits package that meets varied personal and…