Director, Development Strategy & Operations
Listed on 2026-02-16
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Management
Program / Project Manager -
Business
Overview
The Director, Development Strategy & Operations role will be focused on delivering the near- and long-term objectives of the R&D Leadership Team as Alnylam delivers the next wave of transformational medicines.
Reporting to the Executive Director, Development Strategy, Operations, & Portfolio, this role will have broad responsibility for strategic planning and operational delivery within Clinical Development. This individual will drive high-priority projects for the Development organization, facilitate effective prioritization and decision-making, and serve as a thought-partner and executor for senior leaders in the Clinical Development organization (e.g., Pipeline Delivery & Clinical Operations, Clinical Research, Quantitative Sciences).
As a partner to senior leaders Clinical Development, this role requires a highly resourceful person with strong emotional intelligence, self-motivation, proven cross-functional collaboration abilities, and the ability to manage ambiguity and thrive in a fast-paced environment.
Key Responsibilities- Enable a strong connection between the week-to-week operations of the Development and the long-term enterprise strategic roadmap
- Support R&D senior leaders in identifying, scoping, organizing, leading execution, and monitoring progress on priority initiatives (e.g., accelerating cycle times and speed to market)
- Contribute to above-asset and portfolio-wide analyses and initiatives such as disease area strategies, portfolio scenario planning and portfolio prioritization, strategic resource planning and management, etc.
- Drive corporate planning deliverables (annual goal setting, annual investment planning, long-range planning) via thought-partnership with senior leaders, delivering analyses, and running a tight process in coordination with other expertise areas (e.g., Finance)
- Facilitate effective decision-making and follow-through on actions, e.g., for pipeline Governance meetings and priority initiatives steering committees
- Be a trusted thought-partner and problem-solving partner with senior R&D Leaders and the Executive Director, R&D Strategy, Operations, & Portfolio
- Prepare analyses, gather and structure data, structure ambiguous problems, and distill into executive-level communications
- Bachelor s degree in scientific or business discipline; MBA or PhD preferred
- 10+ years of experience, 7 of which in the biotechnology, pharmaceutical, and/or management consulting or professional services, with experience in Clinical Development and R&D
- Experience working on high-visibility projects with frequent engagement with senior stakeholders
- Excellent problem solving and execution skills
- Ability to manage ambiguity and multitask
- Strong project management and matrix working skills
- Ability to build trust and effective working relationships with colleagues across functional groups and levels of seniority (including senior executives)
- Strong written and oral communication skills
- Ability to influence without authority
- Energized by working in a highly entrepreneurial biotech environment
- Intellectual curiosity, adaptability, and desire to learn and continually build skills
$ - $
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k) with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.
We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
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