Clinical Program Manager, Cambridge, MA
Listed on 2026-07-09
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Management
Project & Program Management, Operations Management, Healthcare Management
Clinical Program Manager, Cambridge, MA
Isomorphic Labs (Iso Labs) is developing and applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines. The company's ambitious mission is to one day solve all disease.
Iso Labs has built multiple cutting-edge AI models that power our unified drug design engine, which can tackle a broad spectrum of disease areas and modalities. This breakthrough technology will transform how we design new drug candidates and bring new potential medicines to patients. Come and be part of an interdisciplinary team driving groundbreaking innovation. You will play a meaningful role in achieving our ambitious goals, while being a part of an inspiring and collaborative culture.
Together, let's build the future of medicine at Isomorphic Labs.
Your impactThe experienced Clinical Program Manager will help to lead the transition of our internal programs from pre-IND to clinical trial execution. Reporting to the Program Lead, this critical role will work with the cross-functional global team to drive clinical trial execution, managing timelines, risks, budgets and vendor partnerships. They will leverage AI and emerging technologies to ensure efficient outcomes with a high probability of success.
Whatyou will do
- Project planning and execution: Develop and own integrated project plans that track operational strategy, timelines, risks and dependencies across work streams to ensure alignment between clinical objectives and company goals.
- Cross-functional leadership and communication: Act as the central point of contact ensuring high performance and alignment among the cross-functional clinical trial team.
- Lead project team meetings ensuring effective information sharing, decision making and documentation.
- Collaborate with preclinical program managers as well as AI/ML and data science teams to identify and implement new solutions to increase speed, scale and probability of success.
- External Partnerships: Oversee and manage a network of external vendors, CROs, partners and collaborators including budgets, timelines and key deliverables.
- Stakeholder Management: Provide regular updates to leadership and key stakeholders on clinical study execution and portfolio management.
- Proactively and in real-time help teams to problem solve and identify issues that impact key deliverables, timelines and budgets.
Essential:
- You must have a proven track record of managing a clinical program from IND through late stage clinical development, within expected timelines and budgets.
- Experience working cross functionally with key stakeholders internally as well as external vendors and collaborators. Excellence in building relationships in both settings.
- Highly organized with experienced managing large budgets and complex interdependent timelines using project management tools.
- Strong sense of urgency and accountability to operate in a fast-paced environment.
- Flexibility to adapt to changing timelines and priorities.
- Strong leadership and excellent communication skills.
- Willingness and ability to motivate and hold accountable, interdisciplinary teams and vendors. Ensure on time and within budget execution.
- Formal program management qualification (eg PMP)
- Experience working as part of a global team across countries
We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.
Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.
Brave Brave at Iso is about fearlessness, but it's also about initiative and integrity. The scale of the challenge demands nothing less.
Determined Determined at Iso is the way we pursue our goal. It's a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won't wait, so neither should we.
Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It's knowing that transformation is a group project, and remembering that what we're doing will have a real impact on real people everywhere.
Creating an extraordinary companyWe believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.
We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you…
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