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Senior U.S. Payroll Leader — End-to-End, Hybrid (Cambridge

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Alnylam Pharmaceuticals, Inc.
Full Time position
Listed on 2026-08-19
Job specializations:
  • Management
Salary/Wage Range or Industry Benchmark: 133500 - 180600 USD Yearly USD 133500.00 180600.00 YEAR
Job Description & How to Apply Below
Position: Senior U.S. Payroll Leader — End-to-End, Hybrid (Cambridge)

Alnylam Pharmaceuticals, Inc. in Cambridge, MA is seeking a Senior Manager, U.S. Payroll to own end-to-end payroll for all U.S. employees, ensuring accuracy, compliance, and timely delivery in a hybrid role.

You will validate inputs, manage time and attendance, stay current with payroll laws across states, lead audits, and partner with HRIS, Finance, IT and vendors to optimize workflows. The position offers the opportunity to drive scalable payroll processes in a fast-paced environment.

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Position Requirements
10+ Years work experience
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