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Operational Excellence Performance Lead

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Sanofi
Full Time position
Listed on 2026-07-02
Job specializations:
  • Manufacturing / Production
    Operations Manager, Lean Manufacturing / Six Sigma, Change Management
Salary/Wage Range or Industry Benchmark: 133500 - 192833 USD Yearly USD 133500.00 192833.00 YEAR
Job Description & How to Apply Below

Job Title:

Operational Excellence Performance Lead


Location:

Cambridge, MA

About the Job

The Operational Excellence Performance Lead is a key member of the EM&S Operational Excellence team, responsible for fostering the SMS (Sanofi Manufacturing System) mindset within External Manufacturing and Supply operations. This role works transversally with Global Business Units (GBUs) to standardize, simplify, and optimize external manufacturing operations with Contract Manufacturing Organizations (CMOs), leveraging lean and SMS 2.0 principles and tools. The position ensures sustainability of the performance roadmap through a comprehensive upskilling program.

We deliver 4.3billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

Main Responsibilities
  • Performance Roadmap Deployment:
    Coordinate, prepare, animate performance workshops focused on cycle time reduction, yield improvement, complex problem solving, and launch readiness. Lead and coordinate execution of related action plan.
  • Performance Partnership:
    Act as performance partner for one or more EM&S business units by attending leadership team meetings and performance rituals, supporting early detection of performance gaps and improvement opportunities, and driving prioritization and execution of initiatives.
  • Performance Management System:
    Deploy and maintain the EM&S performance management system according to SMS 2.0 standards, including +QDCI, Team Board, and GPS3 board.
  • Operational Excellence Upskilling Program:
    Contribute to SMS upskilling program including training, certification, and coaching activities.
  • Cultural Change Leadership:
    Champion cultural change in continuous improvement, change management, and problem-solving methodologies.
About You
  • Bachelor's degree required.
  • 7+ years of relevant professional experience.
  • Deep knowledge of performance management systems, continuous improvement methodologies, and problem-solving techniques.
  • Proven track record of realizations.
  • Expertise in sterile manufacturing and aseptic filling operations.
  • Expertise in biotech Drug Substance (DS) manufacturing.
  • Performance-oriented mindset with ability to understand and identify key performance drivers.
  • Cross-functional agility with demonstrated ability to operate effectively in matrix environments.
  • Strong communication skills with ability to establish and deliver impactful communications to senior leadership.
  • Coaching and training capabilities with experience developing others through structured support and feedback.
  • Change management and stakeholder engagement capabilities.
  • Fluent in English (written and verbal).
  • Experience working with external partners and Contract Manufacturing Organizations (CMOs) is a plus.
  • SMS certification Intermediate or above (or equivalent Lean/Six Sigma).
  • Experience in training, coaching, and people development is a plus.
Benefits
  • Wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave.
  • Thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
  • Access to cutting‑edge technology and digital, data, and AI‑driven innovation to power industry‑leading performance at speed and scale.
  • Opportunity to shape the future of medicine and vaccine delivery with seamless launches and a resilient global supply.
  • Global platform to transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Salary Range: $ – $

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership, or civil union status, sex, gender, gender identity or expression, affectional or sexual orientation, disability, veteran or military status or liability for military status, domestic violence victim status, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other characteristic protected by law.

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