Director, Access Marketing

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values - be audacious, be curious, be authentic, be engaged, and be accountable - creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine's toughest problems, we encourage you to read the opportunity below.

Amylyx is seeking a Director, Access Marketing, to lead the strategic development and execution of market access resources for multiple customer audiences. Reporting to the Senior Director, Market Access Strategy, this individual will be responsible for access marketing strategy, content development, messaging, and pull-through materials for payers, PBMs, health systems, HCP offices and their staff, and patient services programs for avexitide, the company's lead product candidate.

The role will translate access strategy, customer insights, evidence, reimbursement considerations, and patient support offerings into compelling, compliant materials that help advance patient access.

• Own the development of access marketing strategy, messaging, value narratives, and customer-facing resources for avexitide, supporting market access field teams, patient services, and the field sales team.
• Lead the development of avexitide payer and access marketing resources, including Pre-Approval Information Exchange (PIE) presentations, payer value proposition (PVP) materials, disease education resources, and budget impact models, in close collaboration with HEOR, Medical Affairs, and the National Accounts team.
• Lead the development of access materials, including HCP office staff educational resources and patient services program marketing assets, in strong partnership with Patient Services, Trade, HCP Marketing, and other cross-functional stakeholders
• Use internal and external resources to track, monitor, and improve avexitide coverage across commercial access customers (PBMs and payers) and government customer types (Medicare, Medicaid, VA, DoD, and TRICARE).
• Create PBM, payer, health system, specialty pharmacy, trade, and provider office materials that communicate product value, coverage considerations, reimbursement pathways, affordability support, and patient services offerings.
• Partner with Market Access, Brand Marketing, Patient Services, Medical Affairs, HEOR/RWE, Legal, Regulatory, Compliance, Field Access, Training, and Commercial Operations to ensure materials are accurate, compliant, differentiated, and actionable.
• Use customer insights, payer dynamics, coverage trends, and field feedback to refine access messaging and identify unmet educational needs.
• Manage agency partners and vendors through briefing, content development, review, production, deployment, and measurement.
• Establish success metrics for access marketing initiatives and evaluate effectiveness through field feedback, customer engagement, and business impact indicators.
• Champion materials through medical, regulatory, and legal review.

• Bachelor's degree required; advanced degree such as MBA, MPH, PharmD, or related discipline preferred.
• 8+ years of experience in pharmaceutical/biotech market access marketing, payer marketing, patient services marketing, managed markets, or related commercial roles.
• Experience building payer resources, such as PIE presentations, PVP materials, and disease state education
• Experience building HCP office support and patient services resources, such as prior authorization and appeals kits, medical exception resources, coding, billing, and reimbursement guides.
• Strong experience using access platforms to monitor coverage and policy and building action plans to support launch/post-launch environments.
• Experience with rare diseases, specialty products, launches, or patient support programs preferred.
• Proven ability to develop compliant, customer-facing market access resources from strategy through execution.
• Experience leading agency partners, materials review processes, cross-functional teams, and launch…