Sr. Research Associate, Preclinical Quality Control in Research Analytics

Individual To Support High-Throughput Pre-Clinical Quality Control Workflows

This position requires a highly skilled and motivated individual to support and advance high-throughput pre-clinical quality control (QC) workflows within research analytics. This role is critical to enabling robust, reproducible, and scalable analytical workflows that support method readiness, routine testing and release of both mRNA and lipid nanoparticle (LNP) materials generated within Moderna's research environment.

In this role, the individual will operate at the intersection of hands-on analytical testing, workflow execution, automation-enabled assay support, and cross-functional collaboration. The successful candidate will help execute, troubleshoot, and improve pre-clinical QC analytical workflows while supporting sample testing, data generation, documentation, and method implementation across a dynamic and fast-paced environment.

Depending on experience, the individual will contribute as a strong technical contributor supporting multiple concurrent testing priorities while partnering with cross-functional stakeholders and teams across research. Beyond the immediate responsibilities, the candidate will be provided additional opportunities to support non-QC workflows, pending candidate's competencies and effectiveness in championing the QC arena. Success in this role requires strong scientific judgment, operational discipline, attention to detail, and the ability to deliver high-quality results under accelerated timelines.

Here's what you will do:

You will operate in a highly collaborative and dynamic environment within the research analytics pre-clinical team, supporting analytical workflows that enable high-throughput testing and release of materials across Moderna's mRNA platform. You will be responsible for executing established pre-clinical QC assays, supporting method implementation, troubleshooting assays and equipment issues, and contributing to workflow improvements.

This role requires strong technical execution, disciplined documentation practices, and the ability to collaborate effectively with scientists, automation engineers, stakeholders at various levels, and operational teams. You will balance hands-on laboratory testing with data review, protocol execution, equipment operation, and continuous improvement activities. Below are some highlights that provide more insight into the scope of the role:

• Execute pre-clinical QC analytical workflows to support testing of mRNA and encapsulated mRNA materials in a high-throughput operations environment.
• Perform established analytical assays such as capillary electrophoresis, LC-MS, HPLC/UPLCDLS, RT-PCR and other platform methods as applicable.
• Operate, maintain, and troubleshoot laboratory and automated testing equipment, including Hamilton liquid handling systems, liquid chromatography systems, plate readers, and other analytical instrumentation.
• Prepare samples, reagents, and assay materials to support high-throughput testing workflows.
• Perform data analysis and documentation in accordance with internal procedures and data integrity expectations.
• Support assay troubleshooting, root cause evaluation, and workflow improvements to improve method robustness, reproducibility, and data turnaround time.
• Track sample testing progress using various digital systems and provide timely updates to project and functional stakeholders.
• Support investigations, deviations, and technical assessments by compiling data, summarizing observations, and presenting findings clearly.
• Author, revise, and maintain documentation including research operating procedures, various data reports and summaries, as well as method execution and performance records.
• Contribute to continuous improvement initiatives focused on assay throughput, operational efficiency, sample flow, equipment utilization, and data quality.
• Maintain safe laboratory practices and comply with Moderna safety procedures, documentation standards, and quality expectations.
• Support general laboratory operations, including reagent preparation, inventory management, equipment maintenance, and coordination of supplies as needed.
• Capacity to multi-task and meet aggressive timelines.
• Demonstrate curiosity, accountability, and flexibility while working in a fast-paced, matrixed environment with evolving priorities.

Here's what you'll need (basic qualifications):

• B.S./B.A. 2+ years of experience in biochemistry, molecular biology, bioanalytical sciences, biomedical engineering, chemical engineering, biology, chemistry, or a related scientific discipline with relevant industry experience (2-5+ years for B.S.; 0-3+ years for master's).
• Hands-on experience executing analytical or bioanalytical assays in a quality-focused, or fast-paced research/technical operations environment.
• Strong attention to detail and commitment to high-quality documentation, data integrity, and reproducible execution.
• Ability to independently execute experiments or testing workflows while…