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Senior Research Associate, Mammalian Cell Engineering Operations

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Lila Sciences
Full Time position
Listed on 2026-02-17
Job specializations:
  • Research/Development
    Research Scientist, Biomedical Science
Salary/Wage Range or Industry Benchmark: 80000 - 106000 USD Yearly USD 80000.00 106000.00 YEAR
Job Description & How to Apply Below

Your Impact at Lila

The Senior Research Associate will play a central role in supporting and advancing LILA’s cell-based research programs. This position is highly hands‑on and will focus on the culture and manipulation of a broad range of mammalian cell types, including primary cells. The ideal candidate brings deep practical expertise in building robust and reproducible cell culture workflows and is excited to help develop and transition protocols from manual execution toward more standardized, scalable, and automation‑enabled processes over time.

Experience in cell engineering (Stable Cell line generation) and lentiviral vector (LVV) production is highly desirable.

What You’ll Be Building
  • Design, execute, and optimize stable and transient mammalian cell engineering workflows, including CRISPR-based genome editing, lentiviral vector (LVV) production and titering, and transposase-based systems; experience with primary cell engineering and transduction is strongly preferred.
  • Culture, maintain, and optimize mammalian cell lines and primary cells, applying best-in‑class aseptic technique across thawing, expansion, passaging, cryopreservation, and cell banking, while proactively monitoring culture health and troubleshooting variability.
  • Perform cell-based assays and downstream analytical readouts, including assessments of viability, proliferation, and phenotype using flow cytometry, qPCR, ELISA, and imaging-based approaches; analyze and clearly summarize results to inform program and experimental decisions.
  • Rigorously document experimental protocols, data, and observations in electronic lab notebooks (ELNs), ensuring accuracy, reproducibility, and compliance with internal standards.
  • Support the development and adoption of automation-enabled cell culture and assay workflows, contributing to increased throughput, robustness, and scalability.
  • Collaborate effectively within cross‑functional teams, providing technical input into experimental design, process optimization, and project planning, and contributing to a culture of continuous improvement.
What You’ll Need To Succeed
  • Bachelor’s degree with 4+ years of experience, or Master’s degree with 2+ years of experience, in Biology, Biotechnology, or a related field.
  • Industry‑relevant, hands‑on experience with a strong emphasis on mammalian cell culture and cell engineering.
  • Strong communication and collaboration skills, with the ability to work effectively across cross‑functional teams.
  • Demonstrated excellence in experimental documentation and SOP development, with a strong focus on reproducibility and quality.
  • Proven ability to learn quickly and adapt in a fast‑paced, innovative, and highly collaborative research environment.
Bonus Points For
  • Bachelor’s degree with 4+ years of experience, or Master’s degree with 2+ years of experience, in Biology, Biotechnology, or a related field.
  • Industry‑relevant, hands‑on experience with a strong emphasis on mammalian cell culture and cell engineering.
  • Strong communication and collaboration skills, with the ability to work effectively across cross‑functional teams.
  • Demonstrated excellence in experimental documentation and SOP development, with a strong focus on reproducibility and quality.
  • Proven ability to learn quickly and adapt in a fast‑paced, innovative, and highly collaborative research environment.
About Lila

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method. We are introducing scientific superintelligence to solve humankind’s greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before.

Learn more about this mission a.ai.

Compensation

We expect the base salary for this role to fall between $80,000- $106,000 USD per year
, along with bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact.

We’re All In

Lila Sciences is committed to equal employment opportunity…

Position Requirements
10+ Years work experience
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