Senior Scientist

United States - Massachusetts - Cambridge

At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development team, dedicated to translating advanced science and innovative technologies into impactful therapies and vaccines. In this role, you will be at the forefront of this effort, ensuring that our daily activities align with our unwavering commitment to quality. Your work will accelerate the delivery of best‑in‑class medicines to patients globally, fulfilling Pfizer's commitment to making a meaningful difference in healthcare.

The Internal Medicine Research Unit (IMRU) at Pfizer is seeking a PhD biologist with 2-5 years of postdoctoral experience and expertise in adipose metabolism and obesity for a Senior Scientist position. This position requires a comprehensive understanding of adipose metabolism, physiology and biology, as well as the impact of obesity on normal adipose tissue metabolic functions. Responsibilities include designing and executing both in vivo and in vitro experimentation, culturing murine and human adipocytes, and effectively interpreting and communicating results to multidisciplinary drug discovery teams.

In addition to supporting drug discovery initiatives, candidates are encouraged to publish in high‑impact journals and present their research findings at external meetings. The successful candidate will collaborate daily with a team of innovative scientists within a supportive environment that promotes rigorous scientific inquiry and professional growth in drug development. Strong self‑motivation, exceptional communication and interpersonal abilities, and the capacity to work both independently and collaboratively are essential requirements.

• Apply creative thinking and scientific expertise to identify and validate therapeutic targets for improving weight loss and adipose tissue function.
• Conceptualize, design and execute in vivo and in vitro experiments to support target discovery and active drug programs.
• Maintain awareness of cutting‑edge scientific and technical developments in adipose research and implement them when needed to advance portfolio programs.
• Participate as a member of diverse scientific drug discovery teams to provide adipose and obesity expertise.
• Mentor junior scientists to develop skills essential to the execution of rigorous scientific research.
• Maintain accurate and timely records of experimentation in electronic notebooks and internal systems.
• Build and facilitate collaborations with partners in the academic scientific community, as well as within the Pfizer network of scientists.
• Present research findings to Pfizer colleagues and the scientific community through publication in peer‑reviewed journals and talks and posters at scientific meetings.
• Present and represent research programs to Pfizer leadership.

• PhD with postdoctoral training in metabolic disease research primarily focused on adipose metabolism and physiology.
• Successful record of scientific accomplishments as indicated by scientific publications and presentations at scientific conferences.
• Deep expertise in adipose metabolism and cellular signaling pathways.
• Ability to contribute to multiple projects in parallel with learning agility and scientific rigor.
• Demonstrated ability to review critically available data and to think creatively in formulating novel hypotheses.
• Strong written and verbal communication skills and ability to collaborate effectively in a team setting with scientists working in other disciplines.

• Experience with isotopic and radioactive tracer study design, execution and interpretation.
• Previous experience with adipose inflammation and fibrosis.

Work Location Assignment:
On Premise

The annual base salary for this position ranges from $93,600.00 to $. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share‑based long‑term incentive program. We offer comprehensive and generous…