Postdoctoral Associate, Dorkenwald Lab

REQUIRED:

Ph.D. in neuroscience, computer science, or a related field; experience in machine learning and developing and validating computational analysis workflows; attention to detail; excellent interpersonal, analytical, problem-solving, organizational, documentation, communication, and time-management skills; self-motivation and ability to work independently; and ability to work as part of a tightly knit team.

10/6/2025

POSTDOCTORAL ASSOCIATE, DORKENWALD LAB, McGovern Institute for Brain Research - Dorkenwald laboratory, to develop computational reconstruction, analysis, and modeling approaches for connectomics datasets. The lab develops computational approaches to reconstruct, analyze, and model large-scale connectomes, aiming to uncover organizational principles of neuronal circuits and how circuit structure supports computation. Will lead research on one or more of the following areas:
Automated proofreading & annotation at scale:
Machine learning approaches for error detection, human-in-the-loop proofreading of automated cell reconstructions, active-learning approaches for efficient annotation, and self-supervision approaches for tokenizing image datasets and cell reconstructions;
Circuit analysis & modeling:
Analysis of cortical connectomes, including comparative analyses across ages/regions; hypothesis-driven tests of discovered circuit rules; pair analyses with data-constrained models (e.g., RNNs, dynamical systems) and simulations;
Morphology representation & multi-modal linking:
Learn representations of detailed cell morphologies to link across datasets (within connectomics) and across modalities (e.g., EM Patch-seq) to build multi-modal connectomic resources that provide the basis for analyses that combine, e.g., connectivity with transcriptomic information; and publish in leading venues, maintain high-quality, reproducible code, collaborate across McGovern/BCS and external collaborators, and mentor students.