Senior Scientist, Chemistry and Delivery Science

The Role

We are looking for an accomplished Scientist to spearhead the development of targeted lipid nanoparticle (LNP) formulations within our fast‑moving, cross‑functional R&D organization. In this role you will push the boundaries of LNP self‑assembly, engineer delivery systems for both small‑ and large‑molecule payloads beyond the liver, and apply state‑of‑the‑art analytical techniques to link structure with biological performance.

• Drive research programs on targeted, extra‑hepatic LNP delivery—from hypothesis generation through in‑vitro / in‑vivo evaluation
• Develop and optimize LNP self‑assembly processes; refine composition, payload loading, and surface modifications for tissue and cell‑type specificity
• Independently design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership
• Implement and innovate advanced physicochemical and biophysical characterization methods (e.g., DLS, CryoEM, SAXS, ITC, NMR, nFCM) to elucidate structure–function relationships
• Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations
• Mentor & collaborate with research associates and external partners to meet project milestones

• Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
• Deep expertise in lipid nanoparticle design, formulation, and characterization; hands‑on experience developing targeted or extra‑hepatic LNPs preferred.
• Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment.
• Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast‑paced setting.
• This position is site‑based, requiring you to be at Moderna’s site full‑time. This position is not eligible for remote work.

• Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
• Deep expertise in lipid nanoparticle design, formulation, and characterization; hands‑on experience developing targeted or extra‑hepatic LNPs preferred.
• Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment.
• Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast‑paced setting.
• Clear, concise scientific communication—written and verbal—with a track record of peer‑reviewed publications and/or patents.
• Commitment to inclusive teamwork, continuous learning, and high scientific rigor.
• Experience with high‑throughput methodologies is highly desirable, and familiarity with artificial intelligence and machine learning techniques is considered a strong plus.

Salary range: $ – $.

Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow.

If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission everyday, please apply!

Moderna is an E‑Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.