Process Development Senior Scientist

Process Development Senior Scientist

In this vital role you will join the Drug Substance Technologies – Synthetics (DSTS) group within Process Development at our Cambridge, Massachusetts site. The DSTS organization is responsible for inventing, developing, and implementing innovative drug‑substance manufacturing processes and technologies that advance Amgen’s growing portfolio of small‑molecule and hybrid therapeutics.

• Design and develop synthetic routes and scalable chemical processes for the manufacture of synthetic and hybrid drug substances
• Develop safe, robust, efficient, and cost‑effective manufacturing processes suitable for clinical and commercial production
• Advance enabling technologies that accelerate pharmaceutical development and improve sustainability, efficiency, and process robustness
• Support cGMP manufacturing activities and assist with technology transfer efforts to internal manufacturing sites and external contract manufacturing organizations (CMOs)
• Build process understanding through experimentation, process characterization, modeling, and data analysis to ensure consistent process performance
• Contribute to cross‑functional drug‑substance development teams by providing technical expertise, experimental data, scientific recommendations, and clear documentation
• Collaborate across disciplines to support regulatory filings and author technical sections of regulatory documentation
• Stay current with advances in synthetic organic chemistry, process chemistry, and related technologies, and apply new scientific insights to ongoing programs
• Effectively collaborate within multidisciplinary teams that include chemists, engineers, analytical scientists, and other technical experts
• Independently manage project activities and deliver high‑quality results within established timelines

• Doctorate degree (PhD, Pharm
  
  D, or MD) with relevant post‑doctoral experience, completed by August
  2026; or Master’s degree and 3years of scientific experience; or Bachelor’s degree and 5years of scientific experience

• Ph.D. in Organic Chemistry with expertise in total synthesis, reaction methodology, mechanistic chemistry, and/or process development
• Postdoctoral experience in academia or the pharmaceutical/biotechnology industry
• Experience with ADCs or peptides
• Demonstrated track record of scientific innovation through peer‑reviewed publications, patents, and/or conference presentations
• Strong problem‑solving skills and ability to work effectively in a dynamic, interdisciplinary research environment
• Excellent written and verbal communication skills, with strong organizational and time‑management abilities
• Ability to manage multiple priorities and drive complex projects to completion
• A research summary submitted with the CV is strongly encouraged

Salary: USD–per year (actual salary will vary based on experience and qualifications). Additional compensation may include a discretionary annual bonus, stock‑based long‑term incentives, and a comprehensive Total Rewards Plan.

• Comprehensive employee benefits package: retirement and savings plan with generous company contributions, group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts
• Discretionary annual bonus program (or sales‑based incentive plan for field sales representatives)
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Please contact us to request accommodation.

Sponsorship for this role is not guaranteed.