Scientist, Oncology Bioinformatics

Role

This role will support Moderna’s oncology pipeline by contributing computational analyses across research and preclinical development. You will work at the intersection of antigen discovery, tumor immunology, and multi‑omics data analysis, applying established and emerging computational approaches to help characterize tumor biology and immune responses.

Analyze and integrate multi‑omics datasets (e.g., WES/WGS, RNA‑seq, single‑cell) to characterize tumor antigen landscapes.

Apply computational methods to support antigen discovery efforts and investigate tumor‑immune interactions and underlying mechanisms.

Leverage internal and public datasets (e.g., TCGA, GTEx, IEDB) for biomarker exploration and hypothesis generation.

Develop and maintain reproducible analysis workflows using Python, R, and cloud‑based infrastructure (e.g., AWS).

Collaborate with cross‑functional teams in immunology, oncology, and translational research to support experimental design and data interpretation.

Communicate results clearly through presentations, summaries, and documentation to support team decision‑making.

• Ph.D., or M.S. with 4+ years of experience, in Bioinformatics, Computational Biology, or a related field.
• Experience with high‑throughput sequencing data analysis, including DNA‑seq and RNA‑seq.
• Proficiency in Python and/or R for data analysis.
• Experience working in cloud environments (e.g., AWS).
• Demonstrated ability to apply computational approaches to biological or early‑stage translational research problems.
• This position is site‑based; full‑time presence at Moderna’s site is required.

• Exposure to immuno‑oncology, cancer vaccines, tumor immunology, or computational immunology.
• Familiarity with neoantigen prediction approaches, including HLA typing and peptide‑MHC binding tools (e.g., NetMHCpan).
• Experience with immunogenomics resources (e.g., IEDB, TCGA).
• Strong collaboration and communication skills in a team‑oriented environment.

• Healthcare coverage, including voluntary benefit programs.
• Well‑being support such as fitness, mindfulness, and mental health.
• Family planning benefits (fertility, adoption, surrogacy).
• Paid time off, including vacation, volunteer days, sabbatical, global recharge days, and discretionary year‑end shutdown.
• Savings and investment opportunities.

Salary range: $ – $. This represents the lowest to highest salary we, in good faith, believe we would pay for this role at the time of posting.

Moderna is a smoke‑free, alcohol‑free, and drug‑free work environment. Moderna is an E‑Verify Employer in the United States and considers qualified applicants regardless of criminal histories, consistent with legal requirements. Reasonable accommodations are available for qualified job applicants with disabilities. Equal opportunity for all employees and qualified applicants is non‑discriminatory for race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other characteristic protected under applicable law.