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US_Scientist III; R&D

Job in Cambridge, Middlesex County, Massachusetts, 02142, USA
Listing for: The Fountain Group LLC
Full Time position
Listed on 2026-06-04
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Biotechnology, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 57.46 USD Hourly USD 57.46 HOUR
Job Description & How to Apply Below
Position: US_Scientist III (R&D)

The Fountain Group is currently seeking a  III (R&D) for a prominent client of ours. This position is located ails for the position are as follows:

Scientist III (R&D)

Location:

Onsite
Pay Rate: $57.46/hr
Duration: 6 Months (With Possible Extension/Hire)

Job Description

Seeking a Scientist III to support antibody-oligonucleotide conjugate drug discovery within a medicinal chemistry research environment. This role focuses on the design, synthesis, purification, and characterization of functionalized oligonucleotides and bioconjugates supporting innovative therapeutic programs. The scientist will collaborate with multidisciplinary teams to advance conjugation technologies and optimize synthetic methodologies.

  • Design, synthesize, and purify functionalized oligonucleotides for antibody bioconjugation applications
  • Develop and optimize synthetic organic chemistry and bioconjugation strategies
  • Execute reaction design, optimization, and scale-up activities for complex molecular constructs
  • Characterize synthesized compounds using modern analytical and spectroscopic techniques
  • Evaluate synthetic feasibility and develop innovative solutions to complex chemistry challenges
  • Support antibody-oligonucleotide conjugate platform development through experimental execution and data analysis
  • Present scientific findings and technical recommendations to project teams
  • Contribute to drug discovery programs in a multidisciplinary research environment
Education
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or related field with 1–3 years of relevant experience; OR
  • M.Sc. in Organic Chemistry, Medicinal Chemistry, or related field with 8+ years of relevant experience
Required Skills
  • Synthetic organic chemistry
  • Medicinal chemistry
  • Oligonucleotide synthesis and modification
  • Bioconjugation chemistry
  • Reaction design and optimization
  • Organic compound purification techniques
  • Compound characterization and structural analysis
  • Analytical chemistry instrumentation
  • Parallel reaction synthesis
  • Experimental design and data interpretation
  • Antibody-oligonucleotide conjugate research
  • Scientific publication and technical presentation experience
Preferred Skills
  • Antibody-drug conjugate (ADC) development
  • Antibody-oligonucleotide conjugate (AOC) drug discovery
  • Drug discovery and development experience in industry
  • Conjugation technology development
  • Cross-functional collaboration within pharmaceutical R&D
  • Process optimization for synthetic and bioconjugation workflows
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