Scientist, Platform and TA Bioinformatics

Overview

The Role Moderna is seeking a highly motivated computational scientist to join a collaborative, multi-disciplinary team supporting computational biology across platform research, therapeutic areas, INT, and development. This role focuses on mRNA sequence design, analysis, visualization, and interpretation of complex biological datasets, enabling sequence engineering workflows and enhancing the tools that support them.

• Conduct mRNA sequence optimization to support platform mRNA sequence orders.
• Install IDR (Identity & Ratio) sequences for high-priority programs and candidates advancing toward Lead Nomination.
• Support the day‑to‑day sequence engineering codebase and collaborate on integration of mRNA sequence engineering algorithms into platform applications.
• Generate hypotheses and execute analyses to improve sequence engineering optimization algorithms, including retrospective analyses and model performance assessments.
• Provide modeling and programming support for scientific work streams related to mRNA design, including collaboration on manufacturability‑focused efforts.
• Explore, evaluate, and implement new computational approaches that improve mRNA synthesis success and manufacturability outcomes.
• Improve existing repositories through runtime optimization, code refactoring, and maintenance of technical debt across sequence engineering and complexity rules codebases.
• Develop internal tools for interacting with APIs and systems related to mRNA sequence workflows.
• Communicate results and recommendations clearly to cross‑functional collaborators.

• BS/BA degree.
• 8+ years of experience in algorithm development, computational biology, bioinformatics, or mRNA‑related scientific computing.
• Demonstrated knowledge of genetics and molecular biology, particularly relating to mRNA.
• Experience working with biological datasets and computational analyses.
• Proficiency in at least one programming or scripting language, such as Python and/or R.
• Strong written and oral communication skills.

• M.S. with 4–5 years of relevant experience, or Ph.D. with 0–2 years of experience in bioinformatics, computational biology, or a related field.
• Ph.D. candidates should demonstrate experience applying computational methods to real‑world or production‑relevant biological problems.
• Experience with mRNA sequence optimization and related algorithm development.
• Ability to generate and test hypotheses using complex biological datasets.
• Experience supporting or improving scientific codebases, including refactoring, runtime improvement, and maintenance.
• Ability to understand previously implemented algorithms and improve or extend them thoughtfully.
• Experience building internal tools or workflows to support scientific or operational teams.
• Strong problem‑solving skills and the ability to draw clear conclusions from complex datasets.
• Ability to communicate effectively with both technical and non‑technical collaborators.
• Ability to manage multiple projects and priorities in a fast‑paced environment.
• Meticulous attention to detail and a strong sense of ownership.

• Salary range: $ – $.
• Salary placement within the range depends on competencies, education, qualifications, certifications, experience, skills, performance, and business or organizational needs.
• Eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
• Best‑in‑class healthcare coverage and voluntary benefit programs.
• Well‑being support: fitness, mindfulness, mental health.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Generous paid time off: vacation, volunteer days, sabbatical, global recharge days, discretionary year‑end shutdown.
• Savings and investment opportunities and location‑specific perks.

Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

Moderna is an E‑Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Applicants requiring accommodations should contact the Accommodations team.