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Principal Cheminformatics Scientist - Drug Discovery

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Newton Colmore Consulting
Full Time position
Listed on 2026-06-22
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Biotechnology, Biomedical Science
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below

Principal Cheminformatics Scientist – Drug Discovery

Newton Colmore is working for a start‑up drug discovery biotech and we are assisting them in their search for a cheminformatics expert to join their research team.

The company is seeking an experienced Cheminformatics Scientist to join their multidisciplinary team in Boston, MA and help run their cheminformatics function. As a key member of their research and development team, you will leverage your expertise in computational chemistry and data analysis to support drug discovery efforts and advance their pipeline of therapeutic candidates.

There will also be the possibility of growing a larger cheminformatics team around you, depending on the progress the company makes with their technology.

Responsibilities
  • Develop and implement cheminformatics tools and algorithms to analyze chemical data, predict compound properties, and facilitate drug design workflows.
  • Collaborate with interdisciplinary teams of chemists, biologists, and computational scientists to design and optimize small molecule libraries for lead identification and optimization.
  • Utilize computational modelling techniques to predict molecular interactions, bioactivity profiles, and ADMET properties of drug candidates.
  • Maintain and enhance databases, software platforms, and data visualization tools for chemical and biological data management and analysis.
Qualifications

To be considered for this role you will ideally have the following;

  • Ideally educated to PhD-level in Computational Chemistry, Cheminformatics, Bioinformatics, or related field.
  • Experience in cheminformatics or computational chemistry, preferably within a start-up environment in industry.
  • Proficiency in programming languages such as Python, R, or Java, and experience with cheminformatics software packages (e.g., RDKit, Open Eye, Chem Axon).
  • Strong understanding of chemical informatics principles, molecular modeling techniques, and structure-activity relationship (SAR) analysis.

The company are open on seniority level and can tailor the role to suit the right candidate's experience level and so do get in touch even if you feel you are either too junior or senior for the role.

The company are offering tailored packages for the right candidate that will match your expectations and experience level. This comes with a comprehensive list of benefits along with the chance to build your own team.

To find out more, make a confidential application now and Matt Lowdon, our Head of Biotechnology and Therapeutics will be in touch with more details.

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