Senior Associate Scientist LNP Process Development

Senior Associate Scientist (EG90 Lvl2), LNP Process Development Position Summary

Bristol Myers Squibb is seeking a motivated and detail‑oriented Senior Associate Scientist to join our LNP Process Development team in Cambridge, MA. The LNP PD team works to develop, characterize, and implement robust preclinical and clinical manufacturing processes to support Bristol Myers Squibb's pipeline of products. This role is specifically focused on LNP process development, with responsibilities spanning early process development through clinical manufacturing support.

This is an excellent opportunity for an early‑career scientist to grow within a dynamic, fast‑paced environment. The successful candidate will support planning and execution of laboratory studies and contribute to protocols, technical reports, and regulatory documentation under the guidance of senior team members.

• Execute hands‑on laboratory experiments focused on LNP process development and scale‑up from bench to pilot scale
• Design and perform experiments for optimization and characterization of targeted lipid nanoparticles using structured approaches in both upstream and downstream unit operations (i.e. QbD principles, DoE)
• Contribute to the authoring and review of technical protocols, experimental reports, and batch records in support of early‑to‑late‑stage development activities
• Perform routine analytical testing to assess LNP conjugation, particle size, encapsulation and concentration
• Analyze and interpret experimental results, present findings to senior scientists and project teams
• Collaborate with internal R&D, analytical development, and manufacturing to advance BMS's LNP pipeline
• Support interactions with manufacturing partners, including review of technical documents and participation in technology transfer activities as needed
• Maintain accurate and complete laboratory notebooks and documentation in compliance with internal quality standards

• BS with 2+ years of industry experience, or MS with 0–3+ years of relevant experience, in Chemical Engineering, Biomedical Engineering, Biochemistry, or a related scientific discipline
• Hands‑on experience with LNP formation techniques both at small scale and at large scale
• Familiarity with analytical tools used to assess LNP quality, including ribogreen for measuring encapsulation efficiency, and DLS for measuring particle size
• Basic understanding of LNP formation unit operations
• Strong laboratory fundamentals and attention to detail; comfortable working with bench‑top equipment including nanoparticle formation equipment and UF/DF skids
• Ability to organize and analyze experimental data, identify trends, and clearly communicate results to team members
• Exposure to GMP principles or cGMP environments is a plus but not required
• Experience with design of experiments (DoE) or statistical analysis software is a plus
• Ability to travel internationally up to 10% of the time

Cambridge - MA - US: $96,010 - $116,339

The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job‑related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental and vision care.
• Well‑being Support: Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support and survivor support.

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with…