Computational Research Scientist​/Sr. Scientist

Overview

In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drive research projects scientifically and determine the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, the contribution is essential to the conceptual and scientific success of the project. Assist the PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary.

No

• Make proficient intellectual contributions to scientific strategies of the group/lab and play a leadership role by acting as a subject matter authority in the field.
• Contribute to the design and execution of experiments and/or research projects.
• Exercise judgment in selecting methods and technologies to obtain results.
• May collaborate with external researchers and/or receive external project funding support.
• Present results and prepare publications.
• May assist the PI in the training and supervision of other staff.

Doctorate in a related field of study required.

No

Previous research experience (inclusive of graduate and postdoctoral experience) 5-7 years required.

• Excellent research skills.
• Demonstrated evidence of specific scientific competence in the field.
• Demonstrated broad knowledge of the field.
• Evidence of potential for scientific creativity and original thought.
• Ability to exercise independent judgment and leadership.
• Ability to contribute to publications.

The DeKosky Laboratory for Immune Engineering and Drug Discovery is hiring a postdoctoral researcher to advance computational drug design and discovery, including the use of artificial intelligence (AI) and machine learning (ML) techniques. The hired candidate will focus on computational aspects of immune repertoire analyses of antibody functional screening data. These efforts will advance methods for rapid machine learning-based antibody drug design while developing new and improved antibody drug products.

We are looking for enthusiastic individuals that are curious about computational drug discovery and immunology, and want to participate in the exciting world of diving deeply into understanding how computational data and molecular design can be applied to discover new drugs and fight diseases.

The selected candidate will join a dynamic research team at the forefront of antibody engineering. These projects are fully funded by several organizations, including the U.S. National Institutes of Health and collaborative projects with the Bill and Melinda Gates Foundation, with several ongoing efforts and new projects ready to begin.

Seeking a candidate with an MD or PhD with a minimum of two years of post-degree research experience in immunology, biochemistry, biotechnology, bioinformatics, microbiology, or a related field.

• Experience with next-generation sequencing (NGS) and bioinformatic analysis.
• Experience with protein display technologies and antibody engineering.
• Laboratory research supported by multiple funding sources, including the NIH, Department of Defense, the Gates Foundation, and private industry.

A parallel search is underway for a postdoctoral fellow for candidates who do not yet have at least two years of post-degree experience. Interested individuals should contact Dr. DeKosky directly for additional information regarding postdoctoral opportunities.

The salary range for this position is $80,000.00 - $ annually. At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, applicable education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications;

however, it does not encompass all elements contributing to your total compensation package.

In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, and recognition programs designed to celebrate your contributions and support your professional growth.

The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are…