Associate Director - QSP Quantitative Systems Pharmacology

Job Title

Associate Director - QSP Quantitative Systems Pharmacology

Morristown, NJ

At Sanofi, a global health care and pharmaceutical company, modeling and simulation approaches support strategy and critical decision making throughout the various phases of drug development. The Disease Modeling (DM) group at Sanofi is seeking to hire a highly talented Quantitative Systems Pharmacology (QSP) modeling scientist to support its R&D portfolio. The DM group is part of the Quantitative Pharmacology department within the Translational Medicine Unit in the R&D organization of Sanofi.

• Interface with project team in aligning M&S needs and develop QSP strategy to address needs.
• Develop and implement innovative mechanistic modeling strategies to support project team M&S needs.
• Communicate modeling predictions to key stakeholders to inform strategy and decision-making.
• Identify and interpret preclinical and clinical data critical for model development and refinement.
• Stay current with advances in systems pharmacology, disease modeling, and regulatory expectations for model-informed drug development.
• Contribute to abstracts and manuscripts.
• Perform job duties independently with minimal supervision, and mentor others to develop similar capabilities.

• Ph.D. in Biomedical Engineering, Applied Mathematics, Systems Biology/Pharmacology or related fields.
• ≥6 years of hands‑on QSP modeling experience in the pharmaceutical or biotechnology industry, with demonstrated impact on R&D programs.
• Track record of productivity, with evidence of independence in leading scientific projects.
• Strong publication record in QSP modeling commensurate with experience.
• Hands‑on experience with programming languages like Matlab, R, or Julia (Matlab preferred).
• Demonstrated experience creating and using QSP models to directly influence go/no‑go decisions, and competitive differentiation within a pharma setting.
• Deep understanding of disease biology within at least one therapeutic area and experience applying QSP across multiple programs or drug modalities.
• Experience working with heterogeneous datasets, including preclinical and clinical data.
• Experience with best practices for reproducible, well‑documented modeling workflows.
• Proven ability to lead modeling work streams.
• Proven ability to clearly communicate quantitative insights to scientific and non‑scientific stakeholders, tailoring complexity to the audience.

• Mentoring junior scientists.
• Understanding of neurology, neuroinflammation and neurodegeneration.
• Exposure to regulatory interactions or documentation involving MIDD.

Salary range: $ – $. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in company employee benefit programs, including high‑quality healthcare, preventive and wellness programs, at least 14 weeks’ gender‑neutral parental leave, and a wide range of health and wellbeing benefits.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex; gender, gender identity or expression; affectionate or sexual orientation; disability; veteran or military status;

domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

This position is open to U.S. and Puerto Rico residents only.