Senior Associate Scientist LNP Process Development
Listed on 2026-07-06
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Research/Development
Biotech Research, Research Scientist, Pharmaceutical Science/ Research
Senior Associate Scientist (EG90 Lvl2), LNP Process Development
Senior Associate Scientist is seeking a motivated and detail-oriented Senior Associate Scientist to join our LNP Process Development team in Cambridge, MA. The LNP PD team works to develop, characterize, and implement robust preclinical and clinical manufacturing processes to support Bristol Myers Squibb's exciting pipeline of products. This role is specifically focused on LNP process development, with responsibilities spanning early process development through clinical manufacturing support.
Responsibilities- Execute hands‑on laboratory experiments focused on LNP process development and scale‑up from bench to pilot scale
- Design and perform experiments for optimization and characterization of targeted lipid nanoparticles using structured approaches in both upstream and downstream unit operations (i.e. QbD principles, DoE)
- Contribute to the authoring and review of technical protocols, experimental reports, and batch records in support of early‑to‑late‑stage development activities
- Perform routine analytical testing to assess LNP conjugation, particle size, encapsulation and concentration
- Analyze and interpret experimental results, present findings to senior scientists and project teams
- Collaborate with internal R&D, analytical development, and manufacturing to advance BMS's LNP pipeline
- Support interactions with manufacturing partners, including review of technical documents and participation in technology transfer activities as needed
- Maintain accurate and complete laboratory notebooks and documentation in compliance with internal quality standards
- BS with 2+ years of industry experience, or MS with 0–3+ years of relevant experience, in Chemical Engineering, Biomedical Engineering, Biochemistry, or a related scientific discipline
- Hands‑on experience with LNP formation techniques both at small scale and at large scale
- Familiarity with analytical tools used to assess LNP quality, including ribogreen for measuring encapsulation efficiency, and DLS for measuring particle size
- Basic understanding of LNP formation unit operations
- Strong laboratory fundamentals and attention to detail; comfortable working with bench‑top equipment including nanoparticle formation equipment and UF/DF skids
- Ability to organize and analyze experimental data, identify trends, and clearly communicate results to team members
- Exposure to GMP principles or cGMP environments is a plus but not required
- Experience with design of experiments (DoE) or statistical analysis software is a plus
- Ability to travel internationally up to 10% of the time
Cambridge – MA – US: $96,010 – $116,339. The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job‑related knowledge, and experience.
Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit ‑at‑bms/.
Health Coverage:
Medical, pharmacy, dental and vision care. Wellbeing Support:
Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work‑life benefits include:
Paid Time Off. US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays [not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees]). Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non‑Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays.…
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