Senior Analytical Chemist - Solid State Characterization

Senior Analytical Chemist – Solid State Characterization

Location:

Cambridge, MA

Sanofi is seeking a highly motivated individual to join our analytical group as a Senior Scientist for Solid State Characterization. The group is part of the synthetic platform within Global CMC Development and aims to lead in the development of transformative medicines.

• Lead and perform polymorphism studies for synthetic molecules, including polymorph screening, in‑depth physical characterization, and thermodynamic assessment.
• Design and conduct salt selection studies (salt screening, in‑depth physical characterization and stability assessment, etc.).
• Act as the solid‑state representative on development projects to deploy solid‑form selection strategy in collaboration with functions such as Crystallization, Biopharm, and Chemistry.
• Develop and implement analytical methods using equipment including XRPD, DSC, TGA, SEM, Raman, IR, and laser granulometry.
• Provide physical characterization support (e.g., XRPD, PDS, etc.) to internal partner teams.
• Use computational tools to perform crystal structure prediction studies.
• Generate technical reports independently.
• Develop effective collaborations with others within project teams and between analytical groups.
• Introduce innovative analytical approaches to facilitate optimal decision‑making, including automation and AI/modeling integration.
• Promote scientific excellence through internal and external presentations and publications.

Education:

PhD in chemistry, pharmaceutical science, material science, or related fields with a minimum of 3 years of postdoctoral experience in a pharma or biopharma environment.

• In‑depth experience with solid‑state characterization instruments: XRPD, DSC, TGA.
• Expertise in polymorphism/salt selection and understanding of powder and particle properties.
• In‑depth understanding of pharmaceutical solid‑state properties.

• Experience with SEM, Raman, IR, or laser granulometry.
• Demonstrated expertise in crystallography and computational prediction.
• Experience in crystal structure resolution by sc‑XRD.
• Experience in crystallization of synthetic molecules (e.g., crystallization process, single‑crystal growth).
• Established scientific network in the industry and academia.

• Good oral and written communication skills and ability to communicate effectively in individual and group settings.
• Ability to collaborate effectively in a multi‑disciplinary team environment.
• Record of adhering to and promoting lab safety practices.
• Open‑minded, agile, and capable of innovating in a complex environment.

• Thoughtful rewards package that recognizes contribution and amplifies impact.
• High‑quality healthcare, prevention and wellness programs.
• At least 14 weeks gender‑neutral parental leave.
• Opportunities to grow your talent and drive your career, including promotions, lateral moves, and international options.
• Work on the forefront of drug discovery with AI, data & digital platforms.

$ – $ per year, commensurate with experience.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital status, gender, sexual orientation, disability, veteran status, or any other characteristic protected by law.