Senior Scientist II Discovery Bioanalysis, PK Sciences

LI#-Onsite (Lab Based)
Internal

Title:

Senior Scientist II

Location:

Cambridge

This role is based in Cambridge, MA. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.

As a Senior Scientist II in our Translational Medicine Drug Disposition Discovery Bioanalytical group, you will join a dynamic and high-performing team at the Cambridge site. You will provide timely methods and high-quality data reports for drug discovery projects and liaise with partners to ensure smooth workflows and effective communication. We offer a collaborative culture, opportunities for growth, and competitive salaries and benefits.

• Provide internal lab-based bioanalytical support investigating the PK/TK properties of low-molecular-weight and novel modality compounds.
• Responsible for setting up the new LC‑MS workflow by engaging with key stakeholders.
• Provide mentorship and insights for junior associates to support advanced method development for custom discovery PK and PKPD.
• Collaborate as a subject‑matter expert in bioanalysis with biotransformation, in vitro and in vivo colleagues, as well as chemists and biologists with project teams.
• Independently conceive and run complex experiments/workflows that implement project strategy.
• Analyze, write reports and communicate own results in project meetings.
• Implement technologies such as LC‑MS/MS, SFC‑MS/MS or LC‑HRMS for low‑molecular‑weight and novel modality compounds.
• Explore automation and software‑related solutions to increase workflow efficiency.
• Collaborate with our CRO partners for special case custom BA method transfers to the CRO.
• Utilize established networks and build new network connections, including outside of own department.
• Comply with local and Novartis‑specific rules and regulations.

• B.S. (6+ years) or M.S. (4+ years) or Ph.D. (1+ years) of bioanalytical laboratory scientist in biotech or pharma industry.
• Agility to independently perform high‑quality and fit‑for‑purpose bioanalysis within short timelines.
• Emerging scientific leader with good values and behaviors.
• Hands‑on experience in custom method development, variety of sample preparation (SPE, LLE, IMC, etc.) and quantitative analytical methods for LC‑MS (low‑ and high‑resolution) are required.
• Agility to adapt and shift priorities as per business needs.
• Practices efficient time management to work under tight timelines, focuses on deliverables, and effectively prioritizes when designing/undertaking experimental plans.
• High motivation, curiosity and creativity and the ability to thrive in a matrixed work environment and communicate effectively within multidisciplinary teams.
• Good oral and written communication and presentation skills to communicate key results to internal teams.

• Experience with BA data analysis and reporting PK/TK data is highly preferred.
• Proven track record of establishing new lab workflows is preferred.

The salary for this position is expected to range between $98,700 and $183,300 per year. The final salary offered is determined based on relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance‑based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US‑based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time‑off package including vacation, personal days, holidays and other leaves.