Guide RNA Chemistry Scientist : Synthesis & Optimization
Job in
Cambridge, Middlesex County, Massachusetts, 02140, USA
Listed on 2026-07-21
Listing for:
Prime Medicine
Full Time
position Listed on 2026-07-21
Job specializations:
-
Research/Development
Research Scientist, Drug Discovery, Biotechnology, Pharmaceutical Science/ Research
Job Description & How to Apply Below
Prime Medicine is seeking a talented Scientist I with expertise in oligonucleotide chemistry to join our Guide Chemistry team in Cambridge, MA. The successful candidate will lead long guide RNA synthesis, deprotection, purification, and use of Mer Made 12 or Dr.
Oligo synthesizers to support multiple discovery programs for in vivo studies and preclinical development. The role requires strong phosphoramidite chemistry, solid‑phase synthesis, and RNA purification skills, with potential mentoring of
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