Director, Precision Medicine; Cell Medicine

We are seeking to hire a Precision Medicine Scientific Lead to oversee the development and execution of biomarker strategies for novel cell therapies, cell transfer conditioning agents and combinations with bispecific antibodies across multiple disease areas (Oncology and Immunology). In this highly matrixed role, they will design, develop, communicate across levels and operationally implement clinical biomarker strategies to support selected programs in early and late stage drug development.

Clinical biomarker assays include pharmacokinetic assays, mechanism of action, patient stratification assays and pharmacodynamic assays. The candidate will collaborate with teams internal to RCM and more broadly Regeneron or with contract research organizations to develop and implement clinical biomarker assays.

• Work Location:
  
  Cambridge, MA or Tarrytown, NY
• Hybrid: 4 days per week on site

• Program-level Precision Medicine lead that develops and implements the strategic vision for pharmacokinetic, pharmacodynamic, and exploratory biomarkers for clinical studies enabling indication and/or patient selection, early indication of biological activity, and to identify potential novel combinations.
• String collaboration with Biomarker and clinical operation teams to implement specific biomarker and exploratory sample collection and analyses in all relevant clinical studies in selected programs
• Key individual contributor and precision medicine representative to development and Cell therapy characterization teams with a remit to integrate, influence and deliver biomarker strategies from initial concept to execution, data delivery and results interpretation.
• Collaborate with internal Regeneron laboratories and groups (e.g. Bio Analytical, Clinical Pharmacology, Molecular Profiling, CDX, Discovery Research, Analytical Innovations, DMSQ etc.) to develop plan for validation and application of assays in the clinic.
• Accountability for ensuring complex clinical assays used in programs are fit-for-purpose (whether developed and validated internally or externally)
• Collaborate with Discovery Research and product development teams to facilitate appropriate incorporation of Precision Medicine biomarker strategies for molecules in discovery phases (leading to candidate molecule selection) through to the clinic.
• Represent Regeneron externally thorough collaborations and/or presentations.
• Contribute to Clinical Protocol, schedule of Assessments, clinical study reports, technical reports, data agreements, scientific publications and make recommendations to development teams and management

• PhD and 10+ years of experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech industry.
• Experience in clinical assay development, validation and implementation with strong experience in Immunology is preferred.
• The ability to drive, manage, complete and deliver results for complex multi-functional projects
• Excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

For additional information about Regeneron benefits in the U.S., please visit  For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite.

As part of the recruitment…