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Principal Scientist, Computational Protein Design for TCRs & Antibodies

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: RXinsider LTD.
Full Time position
Listed on 2026-08-07
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery
Salary/Wage Range or Industry Benchmark: 142500 - 256500 USD Yearly USD 142500.00 256500.00 YEAR
Job Description & How to Apply Below

Moderna’s Therapeutics Research group seeks a Principal Scientist to lead computational protein design for TCRs and antibodies, partnering with structural biology, directed evolution, and program teams to accelerate platform innovation.

The candidate will advance AI/ML-guided and structure-informed design, build integrated design platforms, and drive development of next-generation therapeutics across modalities, with a focus on safety, develop ability, and assay-informed iteration.

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