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Lead Computational Protein Design for TCRs & Antibodies

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Moderna Therapeutics
Full Time position
Listed on 2026-08-07
Job specializations:
  • Research/Development
    Research Scientist, Immunology Research, Drug Discovery
Salary/Wage Range or Industry Benchmark: 180000 - 240000 USD Yearly USD 180000.00 240000.00 YEAR
Job Description & How to Apply Below

Moderna Therapeutics in Cambridge, MA is seeking a Principal Scientist to lead computational protein design across therapeutic research, focusing on TCRs and antibodies and contributing to broader design efforts. The role requires deep expertise in protein structure, de novo binder design, molecular recognition, and state-of-the-art computational design workflows.

You will partner with structural biology, immunology, translational science, and program teams to advance platform innovation and

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