Postdoctoral Associate, Keating Lab

Postdoctoral Associate, Keating Lab

Postdoctoral Associate, Keating Lab, Biology, to join a small, collaborative peptide design team working at the interface of computation and experiment. Working closely with the Principal Investigator and a computational Research Scientist, the Postdoctoral Associate will serve as the experimental lead on a peptide design campaign that will involve driving the synthesis and testing of designed peptides, evaluating early hits with assays developed and run independently, and reporting findings to colleagues and collaborators through presentations, publications, and patents.

Results and ideas generated in this role will feed directly into peptide optimization and help refine the design methodology. The Keating Lab is a collaborative and stimulating research environment with strong connections between wet and dry lab, bringing together computational biologists building new methods at the interface of structural biology and machine learning and experimentalists studying how proteins recognize their binding partners across a wide range of biological systems.

REQUIRED:

Ph.D. or equivalent terminal degree in Biochemistry, Biophysics, Structural Biology, Chemical Biology, or a related field; record of original scholarship (e.g., peer-reviewed publications, preprints, patents); proven expertise and success in executing and interpreting in vitro biophysical assays (SPR, BLI, ITC, fluorescence polarization, etc.); strong understanding of binding kinetics, thermodynamics, and macromolecular structure; ability to drive research independently while collaborating effectively within a team, and a track record of meeting deadlines;

and fluency in English for scientific communication. PREFERRED:
Experience working with peptides; peptide modification and unnatural amino acids; and protein or peptide design experience.