Cryo-FIB​/SEM Staff Scientist, CryoEM Facility

Position Overview

The MIT Department of Biology seeks a collaborative and highly motivated Cryo-FIB/SEM Staff Scientist to join the CryoEM Facility o. This role is uniquely dedicated to spearheading the adoption of next-generation plasma FIB milling and in situ structural biology at MIT, acting as the primary lead for our newly installed Hydra Bio plasma FIB/SEM.

While the CryoEM Facility supports a wide range of structural biology techniques, this position is focused primarily on advancing our cellular and tissue imaging capabilities. You will lead workflows utilizing fluorescence‑guided targeting via the integrated Delmic METEOR microscope, high‑precision milling, and sample lift‑out. The successful candidate will blend hands‑on Hydra Bio operation, scientific collaboration, and independent method development to shape the future of high‑resolution cryo‑ET and volume EM research in the Cambridge/Boston area.

• Serve as the primary Hydra Bio plasma FIB/SEM expert; provide hands‑on training, experimental design consultation, and active troubleshooting for cryo‑ET and volume EM workflows.
• Spearhead advanced cryo‑FIB/ET methods (e.g., lift‑out, targeted milling) and publish innovative findings in peer‑reviewed journals.
• Partner on projects to deliver expert sample preparation, milling, tomography, and preliminary data processing/reconstruction.
• Perform routine instrument calibrations, coordinate vendor servicing, and oversee lab infrastructure (LN2, data storage).
• Lead facility tours, workshops, and contribute to scientific community engagement.

• Independent authorization to work in the US. Visa sponsorship is not available.