Senior Associate Scientist, Delivery Technology

Senior Associate Scientist, Delivery Technology

The Research Department at Alnylam is seeking a motivated and skilled Senior Associate Scientist to join our innovative targeted delivery team. The successful candidate will provide critical hands-on support for ligand discovery projects. This role offers an excellent opportunity to work with cutting-edge technologies, contribute to the development of novel therapeutics, and grow within a dynamic and collaborative research environment. This is an onsite lab-based position and will be primarily located in Cambridge, MA.

Key Responsibilities:

• Support ligand discovery campaigns by executing key experiments for ligand discovery, screening, and characterization under the guidance of project leads.
• Perform high-throughput screening and selection using cell-based assay.
• Execute Next-Generation Sequencing (NGS) workflows, including library preparation from single cells.
• Perform standard molecular biology techniques, including PCR, plasmid preparation, and cloning.
• Run and assist in the development of automated, high-throughput screening assays to characterize ligand properties such as affinity, specificity, and internalization.
• Maintain detailed and accurate records of all experimental work and data in electronic lab notebooks.
• Collaborate closely with other members of the cross-functional team to ensure project goals are met.
• Assist in data analysis, interpretation, and the preparation of presentations for internal meetings.

Qualifications:

• BS/MS in Biology, Cell/Molecular Biology or related field with 3-6 years of work experience, preferably in an industrial setting.
• Familiarity with flow cytometry and NGS library preparation is required.
• Hands-on experience with standard molecular biology techniques (e.g., PCR, cloning, DNA/RNA extraction) is required.
• Experience with mammalian cell culture and cell-based assays is highly desirable.
• Direct experience with single B cell isolation and screening technologies is a significant plus.

U.S. Pay Range $80,000.00 - $

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k) with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.

We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.