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Research Associate III
Job in
Cambridge, Middlesex County, Massachusetts, 02140, USA
Listed on 2026-08-23
Listing for:
Q-state Biosciences
Full Time
position Listed on 2026-08-23
Job specializations:
-
Research/Development
Research Scientist -
Healthcare
Job Description & How to Apply Below
- Execute and troubleshoot production and QC of neuronal cultures for Quiver’s multiple customer-based and internal R&D projects.
- Maintain and characterize multiple human iPS cell lines.
- Use transcriptional programming and directed differentiation strategies to produce various types of high-quality human iPS cell-derived neurons, including excitatory, inhibitory, sensory and motor neurons.
- Plate and maintain cultures of human iPS cell-derived neurons in 96-well and 384-well assay formats.
- Carry out RNA and DNA preparations from human cell lines and cultured neurons.
- Perform candidate gene expression analysis using quantitative PCR assays.
- Assess protein expression using immunocytochemistry (ICC) and immunoblotting assays.
- Assist with cell culture lab operations, including inventory, purchasing of lab reagents and supplies, and aliquoting of recombinant protein and lentiviral particle stocks.
- Communicate work progress via technical reports, PowerPoint presentations, and seminars at internal meetings.
- A Master’s degree in biology, cell biology, biotechnology or a related field.
- At least two years of experience with mammalian cell culture (in particular iPS cell-derived neurons) and with DNA/RNA/Protein preparations and readout assays (PCR, qPCR, immunoblotting, and ICC).
- Ability to work independently and in cross-disciplinary teams.
- Excellent oral, written and interpersonal communication skills.
- Experience with methods for human iPS cell differentiation into neurons is a plus.
- Experience with 96/384-well cultures and high-throughput screening is a plus.
- Experience with neuronal preparations from rodent CNS tissues is a plus.
Position Requirements
10+ Years
work experience
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