Scientist, In Vivo Pharmacology

Scientist, In Vivo Pharmacology

Bristol Myers Squibb is seeking a highly motivated Scientist to join the In Vivo Pharmacology group supporting Oncology and Immunology discovery programs. The successful candidate will play a key role in the design, execution, analysis, and interpretation of preclinical in vivo studies to evaluate novel therapeutic candidates. This position requires a strong scientific background in pharmacology, immunology, and/or oncology, as well as the ability to independently drive experimental strategies and collaborate within multidisciplinary discovery teams to advance programs from target validation through candidate selection.

Position Responsibilities

In the role as a Scientist within In Vivo Pharmacology, the ideal candidate will:

In Vivo Study Execution (Oncology & Immunology)

• Design and interpret in vivo studies in murine models of cancer and immune-mediated diseases.
• Perform and oversee in vivo studies, including compound administration, disease induction, tumor implantation, immune cell transfers, longitudinal sampling, and animal monitoring.
• Develop experimental strategies to evaluate pharmacodynamic, efficacy, mechanism-of-action, and combination therapy hypotheses.
• Independently operate and apply imaging technologies, including IVIS, to support efficacy and mechanistic studies.
• Troubleshoot technical and scientific challenges and develop solutions to improve study outcomes.
• Contribute to the optimization and development of novel in vivo models and experimental workflows.

Data Analysis & Reporting

• Analyze and interpret complex datasets using Graph Pad Prism, Excel, and other data analysis tools.
• Integrate in vivo, pharmacodynamic, biomarker, and mechanistic data to generate actionable scientific insights.
• Maintain accurate and timely electronic laboratory notebook (ELN) documentation.
• Prepare and present study results, scientific reports, and project updates to cross-functional teams and leadership.
• Contribute to scientific publications, technical reports, presentations, and regulatory documentation as appropriate.

Cross-Functional Collaboration

• Serve as an in vivo pharmacology representative on Oncology and Immunology project teams.
• Partner with external collaborators and contract research organizations (CROs) to support study execution and data interpretation.
• Contribute scientific insights to project strategy, portfolio discussions, and candidate advancement decisions.

Laboratory Operations & Compliance

• Ensure compliance with BMS policies, IACUC regulations, and animal welfare standards.
• Maintain lab supplies, equipment, and study materials.
• Participate in continuous improvement of in vivo models and workflows.

Experience

Basic Qualifications:

• Bachelor's Degree
• 5+ years of academic and/or industry experience

Or

• Master's Degree
• 3+ years of academic and/or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
• No experience necessary

Preferred Qualifications:

• PhD in Pharmacology, Immunology, Oncology, Cell Biology, or a related life science discipline; or
• MS with 3+ years, or BS with 5+ years of relevant industry experience in in vivo pharmacology.
• Strong scientific expertise in preclinical in vivo pharmacology required.
• Demonstrated experience designing, executing, and interpreting studies in oncology and/or immunology disease models required.
• Hands-on experience with rodent handling, dosing techniques, and biological sample collection required.
• Experience with tumor models, immune-mediated disease models, or both required.
• Proficiency with IVIS imaging and associated data analysis required.
• Strong understanding of experimental design, statistics, and data interpretation.
• Excellent problem-solving skills and scientific curiosity.
• Strong written and verbal communication skills with the ability to effectively present scientific findings.
• Ability to manage multiple priorities and work effectively in a collaborative, fast-paced research environment.
• Industry experience in biotech or pharmaceutical R&D desired.
• Experience working in matrixed, cross-functional teams desired.
• Familiarity with imaging techniques, biomarkers, or molecular assays desired.