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Senior Data Scientist, Predictive Immune Biomarkers

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Merck
Full Time position
Listed on 2026-08-27
Job specializations:
  • Research/Development
    Data Scientist
  • IT/Tech
    Data Scientist, Machine Learning/ ML Engineer, AI Engineer (Applied/Software)
Salary/Wage Range or Industry Benchmark: 145000 - 228000 USD Yearly USD 145000.00 228000.00 YEAR
Job Description & How to Apply Below
  • Multi-omics Integration:
    Integrate multi-omics datasets, including gene/protein expression, spatial transcriptomics, and genotype data.
Job Description

Senior Scientist, Predictive Immune Biomarkers (R3)

Key Responsibilities
  • Foundation Models:
    Build, fine-tune, troubleshoot, and benchmark foundation models for predictive immune biomarker discovery.
  • Multi-omics Analysis:
    Perform quality control (QC) and analysis of different molecular data types including bulk and single-cell RNA-seq (e.g., Limma, Seurat, scanpy), spatial transcriptomics (e.g., Cos Mx, 10x Visium), and proteomics (e.g., OLINK, mass spectrometry-based approaches).
  • Multi-omics Integration:
    Integrate multi-omics datasets, including gene/protein expression, spatial transcriptomics, and genotype data.
  • Documentation:
    Prepare detailed documentation of analysis methods and results in a timely manner.
Required Qualifications
  • Ph.D. in Computer Science, Engineering, Data Science, AI/ML, Bioinformatics, Computational Biology, Genetics & Genomics, Mathematics, Statistics, Physics, Pharmaceutical Science, or related STEM field.
  • A proven track record in multi-omics analysis.
  • Hands-on experience with building, fine-tuning, benchmarking foundation models, preferably for patient stratification related downstream tasks.
  • Fundamental understanding of AI/ML methods, multi-omics data analysis, and omics integration (e.g., RNA-Seq, single-cell RNA-Seq, genotype, spatial transcriptomics, OLINK).
  • Proficiency in R, Python, and Bash, with the ability to establish best practices for reproducible data analyses.
  • Experience with high-performance computing (HPC) systems and AWS Cloud Services (e.g., IAM, S3 buckets).
  • A collaborative and self-motivated individual with a strong work ethic, capable of managing multiple objectives in a dynamic environment and adapting to changing priorities.
  • Excellent written and verbal communication skills.
Preferred Qualifications
  • Good understanding of autoimmune disease biology.
  • Experience in processing and analyzing real-world data.
  • Familiarity with spatial transcriptomics analysis.
  • Knowledge of statistical and population genetics principles.
Required Skills

Autoimmune Diseases, Biomarkers, Cellular Immunology, Computational Biology, Data Science, Genetic Analysis, High Performance Computing (HPC), Immunology Research, Machine Learning (ML), Omics, RNA-Seq, Stratification, Transcriptomics

US And Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

Requirements

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

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The salary range for this role is

$ - $

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location,…

Position Requirements
10+ Years work experience
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