Research Scientist II – Analytical Genomics Laboratory

Key Responsibilities

• Perform experiments using established single-cell and spatial profiling workflows.
• Execute sample preparation, library construction, and sequencing-related protocols per SOPs and study plans.
• Provide input on sample requirements, workflow feasibility, timing, and run setup (under guidance).
• Support troubleshooting and implement approved protocol adjustments; escape technical issues as appropriate.
• Ensure accurate documentation and reproducibility.
• Operate and maintain relevant instruments (routine care and basic troubleshooting).
• Support training of other staff on instrument use and protocol adherence.
• Perform initial data processing for spatial and single-cell genomics datasets using appropriate bioinformatics tools.
• Collaborate with data scientists; contribute to reports and internal presentations.
• Work with local and remote cross-functional teams; communicate experimental status and technical observations.
• Document work accurately; monitor QC measures to ensure data integrity and compliance with lab standards.
• Stay current with advances in single-cell/spatial genomics and help integrate best practices into lab workflows.

• MS (or BS + 2 years experience) in Molecular Biology, Genomics, Biochemistry, or related field (or equivalent experience).
• 1–2 years hands-on experience with spatial transcriptomics and/or single-cell sequencing.
• Knowledge of molecular biology techniques including PCR, qRT-PCR, enzymatic reactions, DNA/RNA purification and manipulation.
• Experience troubleshooting and optimizing protocols (with guidance) for complex genomics assays.
• Knowledge of NGS library preparation and sequencing workflows.

• Experience with tissue processing, imaging, IHC, and microscopy.